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THE INFLUENCE OF VISCERAL OBESITY ON COGNITION IN PATIENTS AFTER CORONARY ARTERY BYPASS SURGERY

https://doi.org/10.15829/1560-4071-2016-4-19-24

Abstract

Aim. To assess the influence of visceral obesity (VO) on cognitive function (CF) of patients after coronary artery bypass surgery (CBG).

Material and methods. Totally, 90 patients included, selected to 2 groups (gr.) by the parameter “waist/hip circumference”. To 1st gr. we included 46 patients with VO, to 2nd — 44 patients without VO. CG assessed via software and hardware by “Status PF” (Kemerovo), the tests on memory, attention, cognition and neurodynamics were done.

Results. In comparison of CF between the groups, in 1 gr. there were lower results comparing to the 2nd before CBG, after 2 weeks and 6 months. In timeline of CF assessment of 1 gr. there was decline of imagery memory (p=0,014) in 2 weeks after CBG. In 6 months after CBG there was improvement of CF in gr. 1 comparing to preoperation data, incl. statistically significant improvement of memory, cognition and neurodynamics. While comparing the CF parameters in 2nd group, there was improvement by “simple analogy” test (p=0,00028) and neurodynamics (the total delays decreased (p=0,033) in the reaction on moving object) even in 2 weeks after CBG. In 6 months after CBG the patients from 2nd group showed improvement of attention, cognition and neurodynamics.

Conclusion. Patients with VO have significantly worse CF and the risk of permanent cognition disorders development after CBG, than those without VO.

About the Authors

Yu. V. Chugunova
Altai State Medical University of the Ministry of Health; Altai Regional Cardiovascular Dispensary
Barnaul


G. A. Chumakova
Altai State Medical University of the Ministry of Health; Research Institute for Complex Issues of Cardiovascular Diseases
Russian Federation

Barnaul;

Kemerovo


Competing Interests:

Нет конфликта интересов



P. A. Ermolin
Altai Regional Cardiovascular Dispensary
Barnaul


A. S. Baranov
Altai Regional Cardiovascular Dispensary
Barnaul


References

1. Panova EI, Martyshina OV, Danilov VA. Pathology associated with obesity: the frequency, the nature and some of the formation mechanisms. Modern Technologies in Medicine 2013; 5(2): 108-15. Russian (Панова Е.И., Мартышина О.В., Данилов В.А. Ассоциированная с ожирением патология: частота, характер и некоторые механизмы формирования. Современные технологии в медицине 2013; 5 (2): 108-15).

2. Ao H, Wang X, Xu F, et al. The impact of body mass index on short- and long-term outcomes in patients undergoing coronary artery graft bypass. PLoS One 2014; 9(4): e95223.

3. S Roriz-Filho J, Sá-Roriz TM, Rosset I, et al. (Pre) diabetes, brain aging, and cognition. Biochimica et Biophysica Acta 2009; 1792(5): 432-43.

4. Chumakova GA, Veselovskaya NG, Gritsenko OV, et al. Metabolic syndrome: challenging and unresolved issues. Russ J Cardiol 2014, 3(107): 63-71. Russian (Чумакова Г.А., Веселовская Н.Г., Гриценко О.В. и др. Метаболический синдром: сложные и нерешенные проблемы. Российский кардиологический журнал 2014; 3(107): 63-71).

5. Yoon DH, Choi SH, Yu JH, et al. The relationship between visceral adiposity and cognitive performance in older adults. Age and Ageing 2012; 41(4): 456-61.

6. Trubnikova OA, Tarasova IV, Barbarash OL, et al. The structure and incidence of cognitive impairment in patients after direct myocardial revascularization. Creative Cardiology 2015; 4: 5-12. Russian (Трубникова О.А., Тарасова И.В., Барбараш О.Л. и др. Структура и частота выявления когнитивных нарушений у пациентов после прямой реваскуляризации миокарда. Креативная кардиология 2015; 4: 5-12).

7. Gunstad J, Lhotsky A, Wendell CR, et al. Longitudinal examination of obesity and cognitive function: results from the Baltimore longitudinal study of aging. Neuroepidemiology 2010; 34(4): 222-9.

8. Veselovskaya NG, Chumakova GA, Kozarenko AA, et al. Adipokines as a modifiable risk factors of cardiovascular disease. Russ J Cardiol 2010; 6: 88-93. Russian (Веселовская Н.Г., Чумакова Г.А., Козаренко А.А., и др. Адипокины как корригируемые факторы риска сердечно-сосудистых заболеваний. Российский кардиологический журнал 2010; 6: 88-93).

9. Tiehuis AM, van der Graaf Y, Mali WP, et al; SMART Study Group. Metabolic syndrome, prediabetes, and brain abnormalities on mri in patients with manifest arterial disease: the SMART-MR study. Diabetes Care 2014. 37(9) :2515-21.

10. Petrova MM, Prokopenko SV, Eremina OV, et al. Long-term results of cognitive disorders after coronary artery bypass surgery. Fundamental research 2015; 1: 814-20. Russian (Петрова М.М., Прокопенко С.В., Еремина О.В., и др. Отдаленные результаты когнитивных нарушений после коронарного шунтирования. Fundamental research 2015; 1: 814-20).

11. Krannich JH, Tobias T, Broscheit J, et al. Diabetes severely affects attentional performance after coronary artery bypass grafting. Journal of Cardiothoracic Surgery 2012; 7:115.

12. Trubnikova OA, Mamontova AS, Syrova ID, et al. Cognitive status of patients with diabetes mellitus type 2 after coronary grafting. Clinical medicine 2015; 8: 39-44. Russian (Трубникова О.А., Мамонтова А.С., Сырова И.Д., и др. Когнитивный статус пациентов после коронарного шунтирования при сахарном диабете 2-го типа. Клиническая медицина 2015; 8: 39-44).

13. Shishkova VN, Osychenko ME. The problem of cognitive deficits in patients with metabolic syndrome. Consilium Medicum 2011; 13(10): 114-18. Russian (Шишкова В.Н., Осыченко М.Е. Проблема когнитивного дефицита у пациентов с метаболическим синдромом. Consilium Medicum 2011; 13(10): 114-18).

14. Lavie CJ, Milani RV, Artham SM, et al. The obesity paradox, weight loss, and coronary disease. Am J Med 2009; 122(12): 1106-14.

15. Kocz R, Hassan MA, Perala PR, et al. The effect of weight loss on the outcome after coronary artery bypass grafting in obese patients. Ann Card Anaesth 2012; 15(3): 190-8.


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Chugunova Yu.V., Chumakova G.A., Ermolin P.A., Baranov A.S. THE INFLUENCE OF VISCERAL OBESITY ON COGNITION IN PATIENTS AFTER CORONARY ARTERY BYPASS SURGERY. Russian Journal of Cardiology. 2016;(4):19-24. (In Russ.) https://doi.org/10.15829/1560-4071-2016-4-19-24

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ISSN 1560-4071 (Print)
ISSN 2618-7620 (Online)