STRUCTURAL VARIABLITY OF LEUCOCYTE GENOME AND ARTERIAL CELLS IN HUMAN ATHEROSCLEROSIS
https://doi.org/10.15829/1560-4071-2017-10-140-146
Abstract
The review is focused on current views on the structural variation of genome of somatic cells as components related to atherosclerosis. The original data presented on the variation spectrum of DNA areas copies in peripheral blood leucocytes and arterial cells in human atherosclerosis. The future directions sketched for the research on somatic cells genome variation with the aim for pathogenetics of multifactorial diseases.
About the Authors
А. A. Sleptsov
SRI of Medical Genetics, Tomsk National Research Center of RAS
Russian Federation
Tomsk
Russian Federation
Tomsk
M. S. Nazarenko
SRI of Medical Genetics, Tomsk National Research Center of RAS; SRI of Complex Issues of Cardiovascular Diseases; Siberian State Medical University (SSMU)
Russian Federation
Russian Federation
V. P. Puzyrev
SRI of Medical Genetics, Tomsk National Research Center of RAS; Siberian State Medical University (SSMU)
Russian Federation
Russian Federation
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For citations:
Sleptsov А.A., Nazarenko M.S., Puzyrev V.P. STRUCTURAL VARIABLITY OF LEUCOCYTE GENOME AND ARTERIAL CELLS IN HUMAN ATHEROSCLEROSIS. Russian Journal of Cardiology. 2017;(10):140-146. (In Russ.) https://doi.org/10.15829/1560-4071-2017-10-140-146
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