IMPACT OF ALCOHOL CONSUMPTION ON SUDDEN CARDIAC DEATH OCCURENCE BY THE REGISTRY GERMINA (REGISTRY OF SUDDEN CARDIAC DEATH OF ECONOMICALLY ACTIVE INHABITANTS IN BRYANSK REGION)
https://doi.org/10.15829/1560-4071-2017-6-108-112
Abstract
Aim. To investigate on the role of alcohol in sudden cardiac death onset (SCD) in economically active inhabitants.
Material and methods. Totally, medical documentation was analyzed, of 1447 economically active inhabitants of Bryansk region in 2012, died due to circulatory causes: the outpatient chart, the inpatient chart, medical death certificate, forensic autopsy, common autopsy. The SCD criteria fulfilled 106 cases. With a unified questionnaire, 26 relatives were surveyed, and medical staff, of those who agreed to respond. In section of 61 corpse, alcohol concentration was measured, with the level of intoxication defined.
Results. By the data from official documents, the part of alcohol cardiomyopathy (ICD I42.6) was 7% from all death cases of suddenly died economically active inhabitants. Outpatient charts and case histories documented the fact of alcohol abuse in 36% of those who requested medical help while alive. Relatives or medical staff, contacted with the died just before the death, confirmed alcohol overconsumption in 42%. Corpse blood investigation revealed 27% specimens with alcohol, and about a half of cases the concentration was at more than moderate intoxication.
Conclusion. Alcohol plays significant role in SCD development in economically active inhabitants. Abuse with the alcohol beverages leads to development and progression of structural and functonal changes in the heart — the substrate for life-threatening ventricular arrhythmias. Also, in many cases alcohol might be the trigger for fatal rhythm disorders.
About the Authors
R. M. LinchakRussian Federation
A. M. Nedbaykin
Russian Federation
E. V. Sementsova
I. A. Yusova
V. V. Strukova
A. N. Kuzovlev
References
1. Zaridze D. Alcohol and mortality in Russia: prospective observational study of 151 000 adults. Lancet. 2014; 9927 (383): 1465-73.
2. Nemtsov AV. Alcohol History of Russia: Modern Period. M.: Book House “LIBROKOM”, 2009, p. 320. Russian (Немцов А . В. А лкогольная история России: Новейший период. М.: Книжный дом “ЛИБРОКОМ”, 2009, 320 с.).
3. Costanzo S, Di Castelnuovo A, Donati МВ, et al. Alcohol consumption and mortality in patients with cardiovascular disease: a meta-analysis. J Am Coll Cardiol. 2010; 55 (13): 1339-47.
4. Mancia G, Fagard R, Narkiewicz K, et al. 2013 ESH/ESC Guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension and of the European Society of Cardiology. J Hypertens. 2013; 31 (7): 1281-357.
5. Shield KD, Soerjomataram I, Rehm J. Alcohol U se and Breast Cancer: A Critical Review. Alcohol Clin. Exp. Res. 2016; 40(6): 1166-81.
6. Praud D, Rota M, Rehm J, et al. Cancer incidence and mortality attributable to alcohol consumption. Int J Cancer. 2016; 138(6): 1380-7.
7. Vreede-Swagemakers JJ, Gorgels AP, Weijenberg MP, et al. Risk indicators for outofhospital cardiac arrest in patients with coronary artery disease. J Clin Epidemiol 1999; 52: 601-7.
8. Wu SI, Tsai SY, H uang MC, et al. Risk Factors for Sudden Cardiac Death Among Patients with Alcohol Dependence: A Nested Case-Control Study. Alcohol Clin. Exp. Res. 2015; 39(9): 1797-804.
9. Moulin SR, Mill JG, Rosa WC, et al. QT interval prolongation associated with low magnesium in chronic alcoholics. Drug Alcohol Depend. 2015; 155: 195-201.
10. Shlyakhto EB Arutyunov GP, Belenkov YN, et al. National guidelines for risk identification and prevention of sudden cardiac death. M.: PH “Medpraktika-M”, 2013, p. 152.
11. Russian (Шляхто ЕВ, Арутюнов ГП, Беленков ЮН и др. Национальные рекомендации по определению риска и профилактике внезапной сердечной смерти. М.: ИД “Медпрактика-М”, 2013, c 152).
12. Mostofsky E, Van der Bom JG, Mukamal KG, et al. Risk of Myocardial Infarction Immediately After Alcohol Consumption. Epidemiology. 2015; 26(2): 143-50.
13. Prozorovsky VI, Carandaev IS, Rubtsov AF The organization of the examination of intoxication. Forensic-medical expertise. 1967; 1: 3-8. Russian (Прозоровский В. И., Карандаев И. С ., Рубцов А . Ф. Вопросы организации экспертизы алкогольного опьянения. Судебно-медицинская экспертиза. 1967; 1: 3-8).
14. Linchak RM, Nedbaykin AM Sementsova EV, et al. The frequency and pattern of sudden cardiac death rate of able-bodied population of the Bryansk region. Hermine data register (register of sudden cardiac deaths to workers Bryansk region). Rational pharmacotherapy in cardiology. 2016; 12 (1): 45-50. Russian (Линчак Р. М., Недбайкин А . М., Семенцова Е. В. и др. Частота и структура внезапной сердечной смертности трудоспособного населения Брянской области. Данные регистра ГЕРМИНА (реГистр внЕзапной сеРдечной сМертности трудоспособного населенИя бряНской облАсти). Рациональная фармакотерапия в кардиологии. 2016; 12(1): 45-50).
15. Bigger J. T. Identification of patients at high risk for sudden cardiac death. Am J Cardiol. 1984; 54 (14): 3D-8D.
16. Sokolova OV. The morphological changes in the myocardial tissue after sudden cardiac death from alcoholic cardiomyopathy. Sud. Med. Ekspert. 2016; 59(1): 3-6.
Supplementary files
![]() |
1. Неозаглавлен | |
Subject | ||
Type | Исследовательские инструменты | |
Download
(377KB)
|
Indexing metadata ▾ |
![]() |
2. Неозаглавлен | |
Subject | ||
Type | Исследовательские инструменты | |
Download
(481KB)
|
Indexing metadata ▾ |
![]() |
3. Инфа об авторах | |
Subject | ||
Type | Other | |
Download
(13KB)
|
Indexing metadata ▾ |
![]() |
4. Текст статьи (Исправленный) | |
Subject | ||
Type | Other | |
Download
(B)
|
Indexing metadata ▾ |
![]() |
5. Текст статьи (резюме-исправленный) | |
Subject | ||
Type | Other | |
Download
(53KB)
|
Indexing metadata ▾ |
Review
For citations:
Linchak R.M., Nedbaykin A.M., Sementsova E.V., Yusova I.A., Strukova V.V., Kuzovlev A.N. IMPACT OF ALCOHOL CONSUMPTION ON SUDDEN CARDIAC DEATH OCCURENCE BY THE REGISTRY GERMINA (REGISTRY OF SUDDEN CARDIAC DEATH OF ECONOMICALLY ACTIVE INHABITANTS IN BRYANSK REGION). Russian Journal of Cardiology. 2017;(6):108-112. (In Russ.) https://doi.org/10.15829/1560-4071-2017-6-108-112