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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">russjcardiol</journal-id><journal-title-group><journal-title xml:lang="ru">Российский кардиологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Cardiology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-4071</issn><issn pub-type="epub">2618-7620</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1560-4071-2017-6-108-112</article-id><article-id custom-type="elpub" pub-id-type="custom">russjcardiol-863</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>РОЛЬ АЛКОГОЛЯ В РАЗВИТИИ ВНЕЗАПНОЙ СЕРДЕЧНОЙ СМЕРТИ ПО ДАННЫМ РЕГИСТРА ГЕРМИНА (РЕГИСТР ВНЕЗАПНОЙ СЕРДЕЧНОЙ СМЕРТНОСТИ ТРУДОСПОСОБНОГО НАСЕЛЕНИЯ БРЯНСКОЙ ОБЛАСТИ)</article-title><trans-title-group xml:lang="en"><trans-title>IMPACT OF ALCOHOL CONSUMPTION ON SUDDEN CARDIAC DEATH OCCURENCE BY THE REGISTRY GERMINA (REGISTRY OF SUDDEN CARDIAC DEATH OF ECONOMICALLY ACTIVE INHABITANTS IN BRYANSK REGION)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Линчак</surname><given-names>Р. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Linchak</surname><given-names>R. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м.н., доцент, заместитель директора</p></bio><email xlink:type="simple">ruslanlinchak@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Недбайкин</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Nedbaykin</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к. м.н., главный врач</p></bio><email xlink:type="simple">priem@cardio32.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семенцова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sementsova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-кардиолог</p></bio><email xlink:type="simple">semenova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юсова</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yusova</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>заместитель главного врача</p></bio><email xlink:type="simple">priem@cardio32.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Струкова</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Strukova</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>заместитель главного врача</p></bio><email xlink:type="simple">svv@cardio32.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузовлев</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuzovlev</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м.н., зав. лабораторией</p></bio><email xlink:type="simple">Kuzovlev@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Государственный научно-исследовательский центр профилактической медицины» Минздрава РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Research Center for Preventive Medicine of the Ministry of Health</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГАУЗ «Брянский областной кардиологический диспансер»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Bryansk Regional Cardiological Dispensary</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>НИИ общей реаниматологии им. В.А. Неговского</institution><country>Russian Federation</country></aff><aff xml:lang="en"><institution>V. A. Negovsky SRI of General Reanimatology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>21</day><month>07</month><year>2017</year></pub-date><volume>0</volume><issue>6</issue><fpage>108</fpage><lpage>112</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Линчак Р.М., Недбайкин А.М., Семенцова Е.В., Юсова И.А., Струкова В.В., Кузовлев А.Н., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Линчак Р.М., Недбайкин А.М., Семенцова Е.В., Юсова И.А., Струкова В.В., Кузовлев А.Н.</copyright-holder><copyright-holder xml:lang="en">Linchak R.M., Nedbaykin A.M., Sementsova E.V., Yusova I.A., Strukova V.V., Kuzovlev A.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://russjcardiol.elpub.ru/jour/article/view/863">https://russjcardiol.elpub.ru/jour/article/view/863</self-uri><abstract><sec><title>Цель</title><p>Цель. Изучить роль алкоголя в развитии внезапной сердечной смерти (ВСС) у лиц трудоспособного населения.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Проанализирована медицинская документация 1447 человек трудоспособного возраста Брянской области в 2012г, умерших по причине болезней системы кровообращения: медицинская карта амбулаторного больного, медицинская карта стационарного пациента, медицинское свидетельство о смерти, акт судебно-медицинского исследования трупа, протокол патологоанатомического исследования. Критериям ВСС соответствовало 106 случаев. По унифицированной анкете проводился опрос 26 родственников умерших и медицинских сотрудников, с которыми был установлен контакт. При секционном исследовании 61 трупа изучалась концентрация алкоголя в крови, на основании которой определялась степень алкогольной интоксикации.</p></sec><sec><title>Результаты</title><p>Результаты. По данным официальных медицинских документов, на долю алкогольной кардиомиопатии (код МКБ I42.6) приходится 7% от всех причин смертности внезапно умерших лиц трудоспособного возраста. В амбулаторных картах и историях болезней факт злоупотребления алкоголем зафиксирован у 36% лиц, обращавшихся за медицинской помощью при жизни. Родственники и/или медицинские сотрудники, непосредственно контактировавшие при жизни с умершими людьми, подтвердили злоупотребление алкоголем в 42% случаев. При исследовании трупной крови алкоголь обнаружен в 27% образцов, при этом в половине случаев концентрация алкоголя соответствовала опьянению более чем средней степени тяжести.</p></sec><sec><title>Заключение</title><p>Заключение. Алкоголь играет значительную роль в развитии ВСС у лиц трудоспособного возраста. Злоупотребление спиртными напитками при жизни приводит к развитию и прогрессированию структурно-функциональных изменений сердца — субстрата для жизнеугрожающих желудочковых аритмий. Помимо этого, во многих случаях алкоголь может являться пусковым фактором для развития фатальных нарушений ритма.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To investigate on the role of alcohol in sudden cardiac death onset (SCD) in economically active inhabitants.</p></sec><sec><title>Material and methods</title><p>Material and methods. Totally, medical documentation was analyzed, of 1447 economically active inhabitants of Bryansk region in 2012, died due to circulatory causes: the outpatient chart, the inpatient chart, medical death certificate, forensic autopsy, common autopsy. The SCD criteria fulfilled 106 cases. With a unified questionnaire, 26 relatives were surveyed, and medical staff, of those who agreed to respond. In section of 61 corpse, alcohol concentration was measured, with the level of intoxication defined.</p></sec><sec><title>Results</title><p>Results. By the data from official documents, the part of alcohol cardiomyopathy (ICD I42.6) was 7% from all death cases of suddenly died economically active inhabitants. Outpatient charts and case histories documented the fact of alcohol abuse in 36% of those who requested medical help while alive. Relatives or medical staff, contacted with the died just before the death, confirmed alcohol overconsumption in 42%. Corpse blood investigation revealed 27% specimens with alcohol, and about a half of cases the concentration was at more than moderate intoxication.</p></sec><sec><title>Conclusion</title><p>Conclusion. Alcohol plays significant role in SCD development in economically active inhabitants. Abuse with the alcohol beverages leads to development and progression of structural and functonal changes in the heart — the substrate for life-threatening ventricular arrhythmias. Also, in many cases alcohol might be the trigger for fatal rhythm disorders.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>внезапная сердечная смерть</kwd><kwd>алкоголь</kwd><kwd>регистр.</kwd></kwd-group><kwd-group xml:lang="en"><kwd>sudden cardiac death</kwd><kwd>alcohol</kwd><kwd>registry</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Zaridze D. Alcohol and mortality in Russia: prospective observational study of 151 000 adults. Lancet. 2014; 9927 (383): 1465-73.</mixed-citation><mixed-citation xml:lang="en">Zaridze D. Alcohol and mortality in Russia: prospective observational study of 151 000 adults. 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