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Dyssynchrony cardiomyopathy in patients with Wolff-Parkinson-White syndrome: solved and unsolved problems

https://doi.org/10.15829/1560-4071-2025-6309

EDN: KECQMQ

Abstract

The article presents a review on dilated cardiomyopathy in patients with the Wolff-Parkinson-White syndrome. It is shown that in young children with the Wolff-Par-kinson-White syndrome, the most pronounced pre-excitation on the electrocardiogram and the right septal or right lateral location of accessory atrioventricular pathways, hypotrophy and dyskinesia of the interventricular septum may occur, with subsequent left ventricular dilation and dysfunction. However, these factors are not specific and cardiomyopathy development is possible in patients of any age and with other locations of additional conduction pathways. In addition, the current classifications of cardiomyopathies in children do not include a concept that includes this condition, and there are no criteria for making this diagnosis.

About the Authors

E. O. Kartofeleva
Cardiology Research Institute, Tomsk National Medical Research Center
Russian Federation

Tomsk



L. I. Svintsova
Cardiology Research Institute, Tomsk National Medical Research Center
Russian Federation

Tomsk



O. Yu. Dzhaffarova
Cardiology Research Institute, Tomsk National Medical Research Center
Russian Federation

Tomsk



E. V. Yakimova
Cardiology Research Institute, Tomsk National Medical Research Center
Russian Federation

Tomsk



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Supplementary files

  • The evidence base for the ankle-brachial index has been forming for several decades, and the need for its measurement is covered in many clinical guidelines. However, it turned out to be uninformative in patients with severe arterial stiffness, since it does not allow to detect early arteriosclerosis; in addition, even in limbs with a normal index, microvascular dysfunction may develop.
  • There is a pressing need to find a new tool for assessing blood flow in lower limb arteries. Toe vessels are less susceptible to vascular stiffness, which makes the toe-brachial index an accessible alternative in such a situation.
  • Due to the likelihood of the significant compaction of lower limb arteries, the predictive value of ankle-brachial index may be reduced, while the assessment of toe-brachial index has virtually no such limitations.

Review

For citations:


Kartofeleva E.O., Svintsova L.I., Dzhaffarova O.Yu., Yakimova E.V. Dyssynchrony cardiomyopathy in patients with Wolff-Parkinson-White syndrome: solved and unsolved problems. Russian Journal of Cardiology. 2025;30(9S):6309. (In Russ.) https://doi.org/10.15829/1560-4071-2025-6309. EDN: KECQMQ

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ISSN 1560-4071 (Print)
ISSN 2618-7620 (Online)