Radiation-induced heart disease in patients with chest cancer: opinion on the problem
https://doi.org/10.15829/1560-4071-2025-6018
EDN: POPAQV
Abstract
Post-radiation chest injury is characterized by complications in the lungs and heart. Radiation-induced cardiac and vascular damage has been described by various authors. Currently, there are 5 following main types of heart injury after radiation therapy: pericarditis, cardiomyopathy, coronary artery disease, acquired valvular heart disease and arrhythmias. The scientific community continues to study this group of heart diseases. There are no unambiguous data on the prevention of these conditions. The aim of this work was to summarize current information on the pathogenesis and consequences of post-radiation heart injury.
About the Authors
S. O. Danilenko
Meshalkin National Medical Research Center; Novosibirsk National Research State University
Russian Federation
Competing Interests:
Russian Federation
Novosibirsk
Competing Interests:
none
A. K. Nikolaeva
Novosibirsk National Research State University
Russian Federation
Competing Interests:
Russian Federation
Novosibirsk
Competing Interests:
none
I. Yu. Loginova
Meshalkin National Medical Research Center
Russian Federation
Competing Interests:
Russian Federation
Novosibirsk
Competing Interests:
none
O. V. Kamenskaya
Meshalkin National Medical Research Center
Russian Federation
Competing Interests:
Russian Federation
Novosibirsk
Competing Interests:
none
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Supplementary files
What is already known about the subject?
- One of the serious complications of radiation therapy (RT) is radiation-induced heart disease.
What might this study add?
- The pathogenesis of post-radiation heart injury is described in detail from the point of view of acute and delayed body reactions.
- Modern photon therapy limits the risk of cardiac dysfunction, and proton therapy can reduce it to 2,9%.
How might this impact on clinical practice?
- The data obtained can help in the development of safer and more effective RT protocols to reduce the risk of cardiotoxicity.
- Optimization of cardiac function monitoring in patients after RT can improve their long-term health and survival.
Review
For citations:
Danilenko S.O., Nikolaeva A.K., Loginova I.Yu., Kamenskaya O.V. Radiation-induced heart disease in patients with chest cancer: opinion on the problem. Russian Journal of Cardiology. 2025;30(6S):6018. (In Russ.) https://doi.org/10.15829/1560-4071-2025-6018. EDN: POPAQV
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