SPECIFICS OF MYOCARDIAL INFARCTION IN OBESITY

G. A. Chumakova; A. P. Pokutnev; N. G. Veselovskaya

doi:10.15829/1560-4071-2017-4-75-80

SPECIFICS OF MYOCARDIAL INFARCTION IN OBESITY

G. A. Chumakova, A. P. Pokutnev, N. G. Veselovskaya

https://doi.org/10.15829/1560-4071-2017-4-75-80

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Abstract

The article is focused on the issue of prediction of acute coronary syndrome onset (ACS) and its clinical course specifics in patients with various obesity grades. The phenomenon of “obesity paradox” is taken in ACS, and several possible explanations are given. The data is provided, on the closer relation of the ACS risk with such criteria for obesity as waist circumference and index waist/hip circumference, as these parameters indirectly point on the presence of visceral obesity. The results presented, of the studies on close relation of epicardial fat tissue with its neurohumoral actions in ACS risk.

Keywords

acute coronary syndrome, obesity, visceral adiposity, epicardial fat deposition

About the Authors

G. A. Chumakova

Altai State Medical University of the Ministry of Health; Research Institute for Complex Issues of Cardiovascular Diseases
Russian Federation

Competing Interests: Нет конфликта интересов

A. P. Pokutnev

Research Institute for Complex Issues of Cardiovascular Diseases
Russian Federation

Competing Interests: Нет конфликта

N. G. Veselovskaya

Research Institute for Complex Issues of Cardiovascular Diseases; Altai Regional Cardiological Dispensary
Russian Federation

Competing Interests: Нет конфликта

References

1. Bastien M., Poirier P., Lemieux I., et al. Overview of epidemiology and contribution of obesity to cardiovascular disease. Prog Cardiovasc Dis 2014; 56(4):369-81.

2. WHO. Obesity and overweight. Fact sheet N 311. Ubdated January 2015. Available at: http://www.who.int/mediacentre/factsheets/fs311/en/Checked by 10/08/2016

3. Muromtseva GA, Kontsevaya AV, Konstantinov VV, et al. The prevalence of risk factors noninfectious diseases in Russian population in 2012-2013. Survey ESSAY-RF. Cardiovascular Therapy and Prevention 2014; 13 (6): 4-11. Russian (Муромцева Г.А., Концевая А.В., Константинов В.В., Ильин В.А. и др. Распространенность факторов риска неинфекционных заболеваний в российской популяции в 2012-2013 гг. Результаты исследования ЭССЕ-РФ. Кардиоваскулярная терапия и профилактика 2014; 13(6): 4-11.

4. Berrington de Gonzalez A, Hartge P, Cerhan JR, et al. Body-mass index and mortality among 1.46 million white adults. N Engl J Med. 2010;363(23):2211–9.

5. Flegal KM, Kit BK, Orpana H, Graubard BI. Association of allcause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis. JAMA 2013;309(1):71–82.

6. Kalantar-Zadeh K, Streja E, Kovesdy CP, et al. The obesity paradox and mortality associated with surrogates of body size and muscle mass in patients receiving hemodialysis. Mayo Clin Proc 2010;85(11):991–1001.

7. Surya M, Artham MD, Lavie CJ. Obesity and Hypertension, Heart Failure, and Coronary Heart Disease-Risk Factor, Paradox, and Recommendations for Weight Loss. Ochsner J 2009;9(3):124-132.

8. De Schutter A, Lavie CJ, Patel DA, et al. Obesity paradox and the heart: which indicator of obesity best describes this complex relationship? Curr Opin Clin Nutr Metab Care 2013;16(5):517-24.

9. Oreopoulos A, Padwal R, Norris CM, et al. Effect of obesity on short- and long-term mortality postcoronary revascularization: a meta-analysis. Obesity. 2008;16(2):442–50.

10. Angerås O, Albertsson P, Karason K, et al. Evidence for obesity paradox in patients with acute coronary syndromes: a report from the Swedish Coronary Angiography and Angioplasty Registry. Eur Heart J 2013;34(5): 345–353.

11. Camprubi M, Cabrera S, Sans J, et al. Body mass index and hospital mortality in patients with acute coronary syndrome receiving care in a university hospital. J Obes 2012;2012:5.

12. Bucholz EM, Rathore SS, Reid KJ, et al. Body mass index and mortality in acute myocardial infarction patients. Am J Med 2012;125(8):796–803.

13. Timo´teo AT, Ramos R, Toste A, et al. Impact of body mass index in the results after primary angioplasty in patients with ST segment elevation acute myocardial infarction. Acute Card Care. 2011;13(3):123–8.

14. Aronson D, Nassar M, Goldberg T, et al.. The impact of body mass index on clinical outcomes after acute myocardial infarction. Int J Cardiol. 2010;145(3):476–80.

15. Mahaffey KW, Tonev ST, Spinler SA, et al. Obesity in patients with non-ST-segment elevation acute coronary syndromes: Results from the SYNERGY trial. Int J Cardiol. 2010;139(2):123–33

16. Buettner HJ, Mueller C, Gick M, et al. The impact of obesity on mortality in UA/non-ST-segment elevation myocardial infarction. Eur Heart J 2007;28(14):1694–701.

17. Mehta L, Devlin W, McCullough PA, et al. Impact of body mass index on outcomes after percutaneous coronary intervention in patients with acute myocardial infarction. Am J Cardiol 2007;99(7):906–10.

18. Nikolsky E, Stone GW, Grines CL, et al. Impact of body mass index on outcomes after primary angioplasty in acute myocardial infarction. Am Heart J 2006;151(1):168–75.

19. Wells B, Gentry M, Ruiz-Arango A, et al. Relation between body mass index and clinical outcome in acute myocardial infarction. Am J Cardiol 2006;98(4):474–7.

20. Wienbergen H, Gitt A, Juenger C, et al. Impact of the body mass index on occurrence and outcome of acute ST-elevation myocardial infarction. Clin Res Cardiol. 2008;97(2):83–8.

21. Herrmann J, Gersh BJ, Goldfinger JZ, et al. Body mass index and acute and long-term outcomes after acute myocardial infarction (from the harmonizing outcomes with revascularization and stents in acute myocardial infarction trial). Am J Cardiol. 2014;114(1):9–16.

22. Caroline N. M. Nunes, Marcos F, et al.. Impact of Different Obesity Assessment Methods after Acute Coronary Syndromes. Arq Bras Cardiol. 2014; 103(1):19-24

23. Carmienke S, Freitag MH, Pischon T, et al. General and abdominal obesity parameters and their combination in relation to mortality: a systematic review and meta-regression analysis. Eur J Clin Nutr. 2013;67(6):573-85

24. Tchernof A, Després J-P. Pathophysiology of human visceral obesity: an update. Physiol Rev. 2013;93(1):359-404.

25. Lee MJ, Wu Y, Fried SK. Adipose tissue heterogeneity: implication of depot differences in adipose tissue for obesity complications. Mol Aspects Med. 2013;34(1):1-11

26. Zeller M, Steg PG, Ravisy J, et al. Relation between body mass index, waist circumference, and death after acute myocardial infarction. Circulation. 2008;118(5):482–90.

27. Kadakia MB, Fox CS, Scirica BM, Murphy SA, Bonaca MP, Morrow DA. Central obesity and cardiovascular outcomes in patients with acute coronary syndrome: observations from the MERLIN-TIMI 36 trial. Heart. 2011;97(21):1782–7.

28. National Institutes of Health. Guidelines on Overweight and Obesity: Electronic Textbook. Available at: https://www.nblbi.nih.gov/health-pro/guidelines/current/obesity-guidelines/e_textbook/. Checked by 10.08.2016.

29. Kragelund C, Hassager C, Hildebrandt P, et al. Impact of obesity on long-term prognosis following acute myocardial infarction. Int J Cardiol 2005;98(1):123–31.

30. Yusuf S, Hawken S, Ounpuu S, et al. on behalf of the INTERHEART Study Investigators. Obesity and the risk of myocardial infarction in 27 000 participants from 52 countries: a case-control study. Lancet 2005; 9497 (366):1640–1649.

31. Grzywocz P., Mizia-Stec K., Wybraniec M., Chudek J. Adipokines and endothelial dysfunction in acute myocardial infarction and the risk of recurrent cardiovascular events. J Cardiovasc Med (Hagerstown). 2015; 16(1):37-44.

32. Veselovskaya N.G., Chumakova G.A., Kozarenko A.A. et al. Adipokines as the corrected risk factor of cardiovascular diseases. Russian cardiological journal 2010;6:88-93. Russian (Веселовская Н.Г., Чумакова Г.А., Козаренко А.А. и др. Адипокины как корригируемые факторы риска сердечно-сосудистых заболеваний. Российский кардиологический журнал 2010; 6: 88-93).

33. Comert N, Yücel O, Ege MR, Yaylak B, Erdoğan G, Yılmaz MB. Echocardiographic epicardial adipose tissue predicts subclinical atherosclerosis: epicardial adipose tissue and atherosclerosis. Angiology 2012; 63: 586-90.

34. Yang Y., Li Z., Tao H.F., Qi X.Y. An elevated plasma level of visfatin increases the risk of myocardial infarction. Genet Mol Res. 2014; 13(4):8586-95.

35. Barbarash O, Gruzdeva O, Uchasova E. et al. The role of adipose tissue and adipokines in the manifestation of type 2 diabetes in the long-term period following myocardial infarction. Diabetol Metab Syndr. 2016; 8: 24.

36. Khafaji HA, Bener AB, Rizk NM. Al Suwaidi J. Elevated serum leptin levels in patients with acute myocardial infarction; correlation with coronary angiographic and echocardiographic findings. BMC Res Notes 2012;29(5):262

37. Iacobellis G, Malavazos AE, Corsi MM. Epicardial fat: from the biomolecular aspects to the clinical practice. Int J Biochem Cell Biol 2011; 43: 1651-4

38. Xu Y, Cheng X, Hong K, Huang C, Wan L. How to interpret epicardial adipose tissue as a cause of coronary artery disease: a metaanalysis. Coron Artery Dis 2012; 23: 227-33.

39. Veselovskaya NG, Chumakova GA, Elykomov VA, et al. Risk factors for restenosis after coronary stenting in patients with obesity. Cardiovascular Therapy and Prevention 2013; 3:4-9. Russia (Веселовская НГ, Чумакова ГА, Елыкомов ВА, и др. Факторы риска рестеноза после коронарного стентирования у пациентов с ожирением. Кардиоваскулярная терапия и профилактика 2013;3:4-9).

40. Eroglu S, Sade LE, Yıldırır A, et al. Epicardial adipose tissue thickness by echocardiography is a marker for the presence and severity of coronary artery disease. Nutr Metab Cardiovasc Dis 2009; 19: 211-7.

41. Chumakova GA, Veselovskaya NG, Gritsenko OV, et al. Epicardial obesity as a risk factor for coronary atherosclerosis. Cardiology 2013; 1:51-55. Russia (Чумакова Г.А., Веселовская Н.Г., Гриценко О.В., и др. Эпикардиальное ожирение как фактор риска коронарного атеросклероза. Кардиология 2013;1:51-55).

42. Tanındi A, Kocaman SA, Erkan AF, et al. Epicardial adipose tissue thickness is associated with myocardial infarction and impaired coronary perfusion. Anatol J Cardiol 2015; 15: 224-31.

43. Mahabadi AA, Berg MH, Lehmann N,. et al. Association of Epicardial Fat With Cardiovascular Risk Factors and Incident Myocardial Infarction in the General Population. J Am Coll Cardiol. 2013; 61:1388–95.

44. Wang T, Liu Q, Liu C, et al. Correlation of echocardiographic epicardial fat thickness with severity of coronary artery disease in patients with acute myocardial infarction. Echocardiography. 2014;31(10):1177-81.

45. Altun B, Colkesen Y, Gazi E, et al. Could epicardial adipose tissue thickness by echocardiography be correlated with acute coronary syndrome risk scores. Echocardiography. 2013 Nov;30(10):1130-4.

46. European Guidelines on cardiovascular disease prevention in clinical practice 2016 European Heart Journal 2016; 37:2315-2381.

47. Lopez-Jimenez F, Wu CO, Tian X, et al. Weight change after myocardial infarction—the enhancing recovery in coronary heart disease patients (ENRICHD) experience. Am Heart J. 2008;155(3):478–84.

48. Kang WY, Hwang SH, Hwang SH, et al. Effects of weight change on clinical outcomes in overweight and obese patients with acute myocardial infarction who underwent successful percutaneous coronary intervention. Chonnam Med J. 2012;48(1):32–8.

49. Chumakova GA, Veselovskaya NG. Clinical significance of visceral obesity. Moscow. GEOTAR-Media. 2016. - 160. Russia (Чумакова Г.А., Веселовская Н.Г. Клиническое значение висцерального ожирения. - М.: ГЭОТАР-Медиа, 2016. 160 с.).

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For citations:

Chumakova G.A., Pokutnev A.P., Veselovskaya N.G. SPECIFICS OF MYOCARDIAL INFARCTION IN OBESITY. Russian Journal of Cardiology. 2017;(4):75-80. (In Russ.) https://doi.org/10.15829/1560-4071-2017-4-75-80

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ISSN 1560-4071 (Print)
ISSN 2618-7620 (Online)

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	Title	Неозаглавлен
	Date	2017-03-13

	Title	Рисунок 1
	Type	Исследовательские инструменты
	Date	2017-03-13

	Title	Рисунок 3
	Type	Исследовательские инструменты
	Date	2017-03-13

	Title	Рисунок 4
	Type	Исследовательские инструменты
	Date	2017-03-13

	Title	Названия рисунков
	Type	Исследовательские инструменты
	Date	2017-03-13

	Title	Список сокращений
	Type	Исследовательские инструменты
	Date	2017-03-13

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Russian Journal of Cardiology

SPECIFICS OF MYOCARDIAL INFARCTION IN OBESITY

Full Text:

Abstract

Keywords

About the Authors

References

Supplementary files

Review

For citations:

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