LONG-TERM RESULTS OF THE VALVE-SAVING SURGERY IN MARFAN SYNDROME PATIENTS
https://doi.org/10.15829/1560-4071-2016-11-12-15
Abstract
The main causes of mortality and morbidity in Marfan syndrome patients are cardiovascular complications. The Bentall DeBono operation for long time has been a gold standard treatment for this pathology.
Aim. To present the obvious benefits of valve-saving surgery stimulating for saving of aorta valve (AoV) in dysplasia of connective tissue.
Material and methods. A single-center retrospective analysis was done, of the results of valve-saving operations on the aorta root. All Marfan syndrome patients were included, who had undergone valve-saving operation on AoV in 2007-2015 y. As the valve-saving operation the David method was used, operation of reimplanting of aorta root into prosthesis and supracoronary prosthesing of ascending aorta.
Results. Nine-year freedom from aortic regurgitation more 2 grade in long-term follow-up was 64%. As the a causes for development of aortic valve insufficiency were progressing degenerations of AoV. There were no cases of bleedings and endocarditis. Expected cumulative survival was 63%.
Conclusion. Valve-saving operations are applicable in patients with the syndrome of connective tissue dysplasia. However, the worth of valve-saving operations in Marfan syndrome is questionable. Taken the known data, the studies demanded, with more number of patients and longer follow-up.
About the Authors
D. S. Khvan
Center for Surgery of Aorta, Coronary and Peripheral Arteries, E. N. Meshalkin Novosibirsk Scientific-Research Institute of Circulation Pathology, Novosibirsk, Russia
Russian Federation
Russian Federation
A. M. Chernyavskiy
Center for Surgery of Aorta, Coronary and Peripheral Arteries, E. N. Meshalkin Novosibirsk Scientific-Research Institute of Circulation Pathology, Novosibirsk, Russia
Russian Federation
Russian Federation
D. A. Sirota
Center for Surgery of Aorta, Coronary and Peripheral Arteries, E. N. Meshalkin Novosibirsk Scientific-Research Institute of Circulation Pathology, Novosibirsk, Russia
Russian Federation
Russian Federation
S. A. Alsov
Center for Surgery of Aorta, Coronary and Peripheral Arteries, E. N. Meshalkin Novosibirsk Scientific-Research Institute of Circulation Pathology, Novosibirsk, Russia
Russian Federation
Russian Federation
M. M. Lyashenko
Center for Surgery of Aorta, Coronary and Peripheral Arteries, E. N. Meshalkin Novosibirsk Scientific-Research Institute of Circulation Pathology, Novosibirsk, Russia
Russian Federation
Russian Federation
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Review
For citations:
Khvan D.S., Chernyavskiy A.M., Sirota D.A., Alsov S.A., Lyashenko M.M. LONG-TERM RESULTS OF THE VALVE-SAVING SURGERY IN MARFAN SYNDROME PATIENTS. Russian Journal of Cardiology. 2016;(11):12-15. (In Russ.) https://doi.org/10.15829/1560-4071-2016-11-12-15
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