Preview

Russian Journal of Cardiology

Advanced search

ALTERNATIVE TO Q WAVE DIAGNOSIS USING CARDIAC ACTION POTENTIAL PROPAGATION TIME MEASUREMENT

https://doi.org/10.15829/1560-4071-2016-4-eng-179-186

Abstract

The diagnosis of myocardial infarction is done by ECG through the observation of Q waves in one or more leads. The paper describes the relationship between Q waves and the propagation time of the Cardiac Action potential and a technique by which this time of propagation itself can be measured. Rather than observing the Q wave pathology in its very small peak of the total QRS complex, a more refined method is thus made available for continuous patient observation. This propagation time rises from 15 ms to 35 ms or more in progressive pathological conditions. A simulation has been done which illustrates how the Q wave is generated from the travelling action potential wave in the ventricle. The authors have utilized the easy to use novel EPIC Microelectrodes from Plessey Electronics, which are jelly free and provide easy attachment by simple skin contact. Multiple sensors were placed on the chest and the propagation time was measured by differential voltages between them. An embedded controller was used to pick these signals in digitized form and calculate the time intervals. The measurement procedure is simple and highly non invasive. Records from outpatients with cardiac pathology were taken and it was verified that this AP time increases with the Q wave width. This AP propagation time is a more refined method of observing pathological changes than the Q wave, since progressive changes in cardiac condition can be indicated by changes in the millisecond values. It has been verified that the values match with to the usual Q wave width timings.

About the Authors

S. Ananthi
University of Madras
India

Associate Professor and Head of the Department of Information Technology,

Chennai



V. Vignesh
University of Madras
India
Chennai


K. Padmanabhan
A.C. College of Technology, Anna University
India
Chennai


References

1. Ananthi S. Medical Instruments, New Age International Publishers, 2005.

2. Daskalov IK, Christov II. Automatic Detection of ECG T wave end, Med.& Biol. Engg. and Computing, 1999:37348-54.

3. Laguna P, Jana R, Olmos S, et al. Adaptive Estimation of QRS Complex Wave Features of ECG Signal, Med, &Biol. Engg. and Comp., Jan. 1996: 58-63.

4. Padmanabhan K. Circuit to Explain Cardiac Conduction and Propagation, Med. & Biol. Engg and Control, 1977, 15, 604-610.

5. Stephen Rohr, Role of Gap Junctions in the Propagation of Cardiac Action Potential, Cardiovasc. Res., May 2004.

6. Yan Wang, Yoram Rudy, Action Potential Propagation in in Homogeneous Tissue: Safety Factor and Ionic Disturbances, Am.Jour. Physiol. Heart and Circ., 2000(4), 278.

7. Q wave and Non Q Wave Myocardial Infarction — A Multivariate Analysis, Jour. Pak. Med. Assn., June 1999, p.149-154.

8. Mathhlas Goernig, Benjamin Hoeffling et al, T-Vector and Loop Characteristics Improve Detection of Myocardial Injury After Infarction, Med. & Biol. Engg. and Comp., 2015: 381-6.

9. Padmanabhan K, Ananthi S. Analysis of Fibrillation and Defibrillation to Develop Minimal Energy Defibrillator, Jour. Inst.Engrs.(India), 2008; 89(5).

10. Waxman MB, Berman ND, Downer E. A Method for On-Line Automatic Beat to Beat Digital Display of Cardiac Action Potential Duration, Med. & Biol. Eng. and Control., 1976.

11. McGillvray RM, Wald RW. Measurement of the Maximum Rate of Rise of the Cardiac APMed. & Biol.Engg. and Comp. 1984.

12. Dobra D, Neycheva T, Mudrov N. Simple Two Electrode Biosiganl Amplifier Med. & Biol. Engg. and Computing, 2005 (43), 725-30.

13. Plessey EPIC Micro Electrodes, Plessey Inc., 2013.

14. Wang AY, Rudy Y. Action Potential Propagation in Homogeneous Tissue: Safety Factor and Ionic Disturbances, Am. Jour. Physiol. Heart and Circ., 2000(4), 278.

15. www.oshon.com.


Review

For citations:


Ananthi S., Vignesh V., Padmanabhan K. ALTERNATIVE TO Q WAVE DIAGNOSIS USING CARDIAC ACTION POTENTIAL PROPAGATION TIME MEASUREMENT. Russian Journal of Cardiology. 2016;(4-eng):179-186. https://doi.org/10.15829/1560-4071-2016-4-eng-179-186

Views: 1282


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1560-4071 (Print)
ISSN 2618-7620 (Online)