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МОЛЕКУЛЯРНЫЕ БИОМАРКЕРЫ В ДИАГНОСТИКЕ, СТРАТИФИКАЦИИ РИСКА И ПРОГНОЗИРОВАНИИ ХРОНИЧЕСКОЙ СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТИ

https://doi.org/10.15829/1560-4071-2016-8-86-91

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Аннотация

Классические проявления застойной сердечной недостаточности имеют недостаточно высокую чувствительность и специфичность, что приводит к поздней диагностике и ухудшению прогноза заболевания. Концепция молекулярных биомаркеров получила широкое развитие в последнее десятилетие. К настоящему времени описан ряд биомаркеров, отражающих различные патофизиологические процессы, формирующие звенья патогенеза хронической сердечной недостаточности. Они являются надежным, безопасным и объективным средством диагностики и стратификации риска неблагоприятных событий, дополняющим клинические и инструментальные данные и отражающим особенности механизмов развития и прогрессирования заболевания у конкретного пациента. Данный обзор посвящен обобщению имеющихся доказательных данных о роли биомаркеров в диагностике и стратификации риска.

Об авторах

Е. А. Медведева
ГБОУ ВПО Самарский государственный медицинский университет Минздрава России
Россия

к.м.н., доцент кафедры пропедевтической терапии,

Самара



Е. А. Суркова
ГБОУ ВПО Самарский государственный медицинский университет Минздрава России; Университет Падуи

к.м.н., доцент кафедры пропедевтической терапии, Самара;

Падуя



Л. В. Лимарева
ГБОУ ВПО Самарский государственный медицинский университет Минздрава России

д.б.н., зав. лабораторией иммунологии,

Самара



Ю. В. Щукин
ГБОУ ВПО Самарский государственный медицинский университет Минздрава России

профессор, д.м.н., зав. кафедрой пропедевтической терапии,

Самара



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Для цитирования:


Медведева Е.А., Суркова Е.А., Лимарева Л.В., Щукин Ю.В. МОЛЕКУЛЯРНЫЕ БИОМАРКЕРЫ В ДИАГНОСТИКЕ, СТРАТИФИКАЦИИ РИСКА И ПРОГНОЗИРОВАНИИ ХРОНИЧЕСКОЙ СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТИ. Российский кардиологический журнал. 2016;(8):86-91. https://doi.org/10.15829/1560-4071-2016-8-86-91

For citation:


Medvedeva E.A., Surkova E.A., Limareva L.V., Shchukin Y.V. MOLECULAR BIOMARKERS FOR DIAGNOSTICS, RISK STRATIFICATION AND PREDICTION OF CHRONIC HEART FAILURE. Russian Journal of Cardiology. 2016;(8):86-91. (In Russ.) https://doi.org/10.15829/1560-4071-2016-8-86-91

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