PROGNOSTIC FACTORS AND LONGTERM SURVIVAL OF MYOCARDIAL INFARCTION PATIENTS, COMPLICATED BY EARLY RECURENT ANGINA AND RENAL FUNCTION DECREASE
https://doi.org/10.15829/1560-4071-2016-3-66-69
Abstract
Aim. To study prognosis factors for early postinfarction angina (EPA) in myocardial infarction (MI) and decreased functioning of kidneys, and long-term survival in this group of patients.
Material and methods. Into the retrospective study, 179 patients included, of hospitalized to Moscow clinics, with verified diagnosis MI. Decreased kidney function was defined as GFR <59 mL/min/1,73 m2 . The endpoint was death and complications during hospitalization and all follow up. Time mediana was 18 months.
Results. Totally, 29 cases registered (17,4%) of EPA in MI and known GFR (n=167). Patients with EPA were significantly older (72±11 y. and 62±12 y., respectively, р=0,0001) and among those males predominated (p=0,001). Atrial fibrillation (AF) and diabetes (DM) among EPA patients were significantly more prevalent. In decreased renal function group, EPA was found in 45,5 (n=25), in normal GFR — in 3,5% (n=4, p=0,0001), and the risk of EPA in decreased GFR below 59 mL/ min/1,73 m2 increased 14 times (RR=13,9; 95% CI=4,23-45,65; p=0,001). Long term mortality in EPA group was 30,8% (p=0,001).
Conclusion. PCI improved survival rate in EPA and decreased renal function patients.
About the Authors
N. R. KhasanovRussian Federation
Kazan
O. S. Belkorey
Russian Federation
Moscow
E. N. Dyakova
Russian Federation
Moscow
References
1. Valenzuela LF, Vázquez R, Fournier JA. Prediction of infarction-related artery occlusion and multivessel disease in postinfarction angina. Int J Cardiol. 2007 Feb 14; 115(3): 381-5
2. Bosh X, Theroux P, Waters DD, et al. Early postinfarction ischemia: clinical, angiographic, and prognostic significance. Circulation. 1987; Vol.75 №5. P. 988-95.
3. Lo Y-S, Lesch M, Kaplan K. Postinfarction angina. Progr. Cardiovasc. Dis. 1987; 30: 111-139, Gibson R.S. Non-Q-Wave Infarction: Diagnosis, Prognosis, and Management. Curr. Probl. Cardiol. 1988; 13: 9-72.
4. Vedat K, Hasan A. Angioplasty as early revascularization in acute myocardial infarction. Anadolu Kardiyol Derg 2008; 8 Suppl 2; 77-83.
5. The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). European Heart Journal 2014; 35: 2541-619.
6. Feyter PJ, Serruys PW, Unger F. Bypass Surgery Versus Stenting for the Treatment of Multivessel Disease in Patients With Unstable Angina Compared With Stable Angina Circulation. 2002; 105: 2367-72.
7. Brundage BH, Ullyot OJ, Winokur L, et al. The role of aortic balloon pumping in post infarction angina: a different perspective. Circulation 1980; 62: 116-9.
8. Bajandin NL, Vasil’ev KN, Gendlin GE. Factors determining the prognosis of coronary artery bypass grafting in patients with early postinfarction angina. Russ J Cardiol. 2010; 8 (84): 29-34. Russian (Баяндин Н.Л., Васильев К.Н., Гендлин Г.Е. Факторы, определяющие прогноз аортокоронарного шунтирования у больных ранней постинфарктной стенокардией. Российский кардиологический журнал. 2010; 8 (84): 29-34).
9. Vanholder R, Massy Z, Argiles A, et al. Chronic kidney disease as cuse of cardiovascular morbidity and mortality. Nephrol Dial Transplant 2005; 20(6): 1048-56.
10. Tessone A, Gottlieb S, Barbash IM, et al. Underuse of standard care and outcome of patients with acute myocardial infarction and chronic renal insufficiency. Cardiology. 2007; 108(3): 193-9.
11. Han JH, Chandra A, Mulgund J, et al. Chronic kidney disease in patients with non-STsegment elevation acute coronary syndromes. Am. J. Med. 2006; 119(3): 248-54.
12. Medi C, Montalescot G, Budaj A, et al. Reperfusion in patients with renal dysfunction after presentation with ST-segment elevation or left bundle branch block: GRACE (global registry of acute coronary events). J.A.C.C. Cardiovasc. Interv. 2009; 2: 26-33.
13. Charytan D, Mauri L, Agarwal A, et al. The use of invasive cardiac procedures after acute myocardial infarction in long-term dialysis patients. Am. Heart J. 2006; 152: 558-64.
14. Herzog CA. Dismal long-term survival of dialysis patients after acute myocardial infarction: can we alter the outcome? Nephrol. Dial. Transpl. 2002; 17: 7-10.
Review
For citations:
Khasanov N.R., Belkorey O.S., Dyakova E.N. PROGNOSTIC FACTORS AND LONGTERM SURVIVAL OF MYOCARDIAL INFARCTION PATIENTS, COMPLICATED BY EARLY RECURENT ANGINA AND RENAL FUNCTION DECREASE. Russian Journal of Cardiology. 2016;(3):66-69. (In Russ.) https://doi.org/10.15829/1560-4071-2016-3-66-69