Preview

Russian Journal of Cardiology

Advanced search

Modern features of coronary thrombosis imaging in non-ST-elevation acute coronary syndrome

https://doi.org/10.15829/1560-4071-2025-6298

EDN: NXMUNZ

Abstract

Cardiovascular diseases, in particular ST-elevation (STE-ACS) and non-ST-elevation (NSTE-ACS) acute coronary syndrome remain one of the main causes of death worldwide. Published data indicate that in a number of patients, the cause of NSTE-ACS is infarct-related artery occlusion. In modern medicine, there are both invasive and non-invasive coronary thrombosis imaging methods. The aim of the study was to analyze and systematize the literature data on coronary thrombosis imaging methods. The review was prepared using publications indexed in the PubMed, Google Scholar, Web of Science, and Cyberleninka databases. The search depth was 5 years, starting from 2020. The review is based on summarized data from the most relevant clinical studies, reports, and systematic reviews. The conducted literature analysis showed that both invasive and non-invasive imaging methods have a number of advantages and disadvantages. In this regard, improving these techniques remains an urgent research task.

About the Authors

A. V. Strelkova
National Medical Research Center for Therapy and Preventive Medicine; Odintsovo Regional Hospital
Russian Federation

Moscow, Odintsovo


Competing Interests:

none



M. G. Chashchin
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation

Moscow


Competing Interests:

none



A. Yu. Gorshkov
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation

Moscow


Competing Interests:

none



O. M. Drapkina
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation

Moscow


Competing Interests:

none



A. V. Yurin
Odintsovo Regional Hospital
Russian Federation

Odintsovo


Competing Interests:

none



E. V. Gagarina
National Medical Research Center for Therapy and Preventive Medicine; Medical Research and Educational Center, Lomonosov Moscow State University
Russian Federation

Moscow


Competing Interests:

none



A. S. Tereshchenko
Chazov National Medical Research Center of Cardiology
Russian Federation

Moscow


Competing Interests:

none



References

1. Vaisman DSh, Enina EN. Сoronary artery disease mortality rates in the Russian Federa­tion and a number of regions: dynamics and structure specifics. Cardiovascular Therapy and Prevention. 2024;23(7):3975. (In Russ.) doi:10.15829/1728-8800-2024-3975.

2. Zhuravleva MV, Zyryanov SK, Paleev FN, et al. Contribution of ticagrelor therapy in pati­ents with acute coronary syndrome and patients with myocardial infarction to the achieve­ment of State Program "Health Development" target in Russia as a whole and Rus­sian regions in 2023-2025. Russian Journal of Cardiology. 2024;29(1):5700. (In Russ.) doi:10.15829/1560-4071-2024-5700.

3. Milen`kin BI, Milen`kina SG, Gavrilko AD. Cardio atlas. Clinical cases of acute coronary syndrome. M.: Umnyj doktor, 2022. p. 152. (In Russ.) ISBN: 978-5-6043769-6-6.

4. Khan AR, Golwala H, Tripathi A, et al. Impact of total occlusion of culprit artery in acute non-ST elevation myocardial infarction: a systematic review and meta-analysis. European Heart Journal. 2017;38(41):3082-9. doi:10.1093/eurheartj/ehx418.

5. Hung CS, Chen YH, Huang CC, et al. Prevalence and outcome of patients with non-ST segment elevation myocardial infarction with occluded "culprit" artery — a systemic review and meta-analysis. Critical Care. 2018;22:34. doi:10.1186/s13054-018-1944-x.

6. Barbarash OL, Duplyakov DV, Zateischikov DA, et al. 2020 Clinical practice guidelines for Acute coronary syndrome without ST segment elevation. Russian Journal of Cardio­logy. 2021;26(4):4449. (In Russ.) doi:10.15829/1560-4071-2021-4449.

7. D'Ascenzo F, Biondi-Zoccai G, Moretti C, et al. TIMI, GRACE and alternative risk scores in Acute Coronary Syndromes: A meta-analysis of 40 derivation studies on 216,552 patients and of 42 validation studies on 31,625 patients. Contemporary clinical trials. 2012;33(3):507-14. doi:10.1016/j.cct.2012.01.001.

8. Fox KAA, FitzGerald G, Puymirat E, et al. Should patients with acute coronary disease be stratified for management according to their risk? Derivation, external validation and outcomes using the updated GRACE risk score. BMJ Open. 2014;4:e004425. doi:10.1136/bmjopen-2013-004425.

9. Chernyavskiy AM, Bessonov IS, Badoyan AG, et al. Coronary angiography and sten­ting. Guide. Moscow:GEOTAR-Media, 2022. p. 328. (In Russ.) ISBN: 978-5-9704-7224-8.

10. Chernyak AA, Deshko MS, Snezhiczkiy VA, et al. Percutaneous coronary interventions: intravascular imaging techniques and measurement of intracoronary hemodynamics. Journal of the Grodno State Medical University. 2020;18(5):513-22. (In Russ.) doi:10.25298/2221-8785-2020-18-5-513-522.

11. Endovascular surgery — technology and practices. Kokov LS, Bolomatov NV (eds). M.: RAS, 2021. p. 340. (In Russ.) ISBN: 978-5-907366-26-8.

12. Asadov DA. Comparative evaluation of intravascular ultrasound and optical coherence tomography methods for imaging intravascular structures. International Journal of Inter­ventional Cardioangiology. 2014;36:42-7. (In Russ.) EDN SMFXOR.

13. Mironov VM, Merkulov EV, Tereshchenko AS, et al. Clinical application of a coronary intra­vascular ultrasound study. Vestnik rentgenologii i radiologii. 2013;5:38-49. (In Russ.) EDN RSXIYJ.

14. Ehara S, Kobayashi Y, Yoshiyama M, et al. Spotty calcification typifies the culprit plaque in patients with acute myocardial infarction: an intravascular ultrasound study. Circula­tion. 2004;110(22):3424-9. doi:10.1161/01.CIR.0000148131.41425.E9.

15. Sukmanova IA, Gordeeva DS, Pinaeva AS, et al. Possibilities of using imaging methods of endovascular surgery in patients with coronary artery disease. Bulletin of Medical Science. 2021;4(24):67-80. (In Russ.) doi:10.31684/25418475-2021-4-67.

16. Homorodean C, Leucuta D-C, Ober M, et al. Intravascular ultrasound insights into the unstable features of the coronary atherosclerotic plaques: A systematic review and meta-analysis. European Journal of Clinical Investigation. 2022;52:e13671. doi:10.1111/eci.13671.

17. Arutyunyan GK, Merkulov EV, Tereshhenko AS. Intravascular ultrasound examination: Atlas and guidelines for use in clinical practice. Moscow: Tipografiya "Zetaprint", 2024. p. 132. (In Russ.) ISBN 978-5-93856-804-4.

18. Nasu K, Tsuchikane E, Katoh O, et al. Impact of intramural thrombus in coronary arteries on the accuracy of tissue characterization by in vivo intravascular ultrasound radiofrequency data analysis. The American journal of cardiology. 2008;101(8):1079-83. doi:10.1016/j.amjcard.2007.11.064.

19. Jang IK, Bouma BE, Kang DH, et al. Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound. Journal of the American College of Cardiology. 2002;39(4):604-9. doi:10.1016/s0735-1097(01)01799-5.

20. Kochergin NA, Kochergina AM. Intravascular Ultrasound Studies and the Vulnerable Atherosclerotic Plaque (Literature Review). Medical visualization. 2017;21(4):82-7. (In Russ.) doi:10.24835/1607-0763-2017-4-82-87.

21. Mustafina IA, Zagidullin NSh, Ishmetov VSh, et al. Optical coherence tomography opportunities in detection of coronary plaque morphology. Creative surgery and oncology. 2017;7(1):54-7. (In Russ.) doi:10.24060/2076-3093-2017-7-1-54-57.

22. Trusov IS, Nifontov EM, Biryukov AV, et al. The use of optical coherence tomography imaging of the vascular wall of the coronary arteries before and after stenting. Regio­nal blood circulation and microcirculation. 2019;18(1):77-85. (In Russ.) doi:10.24884/1682-6655-2019-18-1-77-85.

23. Alekyan BG, Boytsov SA, Manoshkina EM, et al. National Results of Revascularization for Acute Coronary Syndrome in 2023. Kardiologiia. 2024;64(11):76-83. (In Russ.) doi:10.18087/cardio.2024.11.n2733.

24. Osinalde EP, Bastante T, Cecconi A, et al. Intracoronary thrombus assessment with cardiac computed tomography angiography in a deferred stenting strategy: the MATURE prospective study (MSCT to Assess ThrombUs REsolution). Coronary Artery Disease. 2023;34(3):167-76. doi:10.1097/MCA.0000000000001225.

25. Morozov SP, Nasnikova IYu, Ternovoy SK. Multispiral computed tomography in a multidisciplinary hospital. Moscow: Nycomed distribution centre, 2009. p. 97. (In Russ.) EDN YMIRDN.

26. Achenbach S, Marwan M. Intracoronary thrombus. Journal of Cardiovascular Computed Tomography. 2009;3(5):344-5. doi:10.1016/j.jcct.2009.06.009.

27. Ternovoy SK, Shabanova MS, Gaman SA, et al. Role of computed tomography in the detection of unstable atherosclerotic plaques of the coronary arteries: comparison of the results of computed tomography and intravascular ultrasound. Russian Electronic Journal of Radiology. 2016;6(3):68-79. (In Russ.) doi:10.21569/2222-7415-2016-6-3-68-79.

28. Anisimov NV, Batova SS, Pirogov Yu A. Magnetic resonance imaging: contrast manage­ment and interdisciplinary applications. Moscow: MAKS Press, 2013. p. 244. (In Russ.) ISBN 978-5-317-04542-5.

29. Borelli C, Berthezene Y, Olteanu B. Subacute Coronary Artery Thrombosis: MRI Findings. Journal of computer assisted tomography. 1997;21(6):962-4. doi:10.1097/00004728-199711000-00020.

30. Kazakova SS, Khazov PD. Magnetik resonance imagining in diagnostics of cerebellar insults. I. P. Pavlov Russian Medical Biological Herald. 2008;16(2):136-41. (In Russ.) EDN JQPXZL.

31. Lombardo P, Lange-Herr N, Hoppe H, et al. Diagnostic accuracy of coronary artery stenosis and thrombosis assessment using unenhanced multiplanar 3D post-mortem cardiac magnetic resonance imaging. Forensic science international. 2023;353:111878. doi:10.1016/j.forsciint.2023.111878.

32. Jansen CH, Perera DD, Makowski MR, et al. Detection of intracoronary thrombus by magnetic resonance imaging in patients with acute coronary syndrome. Journal of Cardiovascular Magnetic Resonance. 2010;12(1):O87. doi:10.1186/1532-429X-12-S1-O87.

33. Bokeriya LA, Goluxova EZ. Clinical cardiology: diagnosis and treatment: textbook: in 3 volumes. Volume 1. Moscow: A. N. Bakulev National Medical Research Center for Cardiovascular Surgery, 2011. p. 662. (In Russ.) ISBN: 978-5-7982-0278-2.

34. Astreiko AV. Prognostic value of systemic inflammatory response markers in the detec­tion of stenosing coronary artery atherosclerosis in patients with chronic coronary heart disease. Meditsinskie novosti. 2022;10(337):8-12. (In Russ.) EDN FUWNBU.

35. Bilgin M, Akkaya E, Dokuyucu R. Evaluation of Inflammatory Markers in Predicting Coronary Complexity: Insights from the SYNTAX II Score in NSTEMI Patients. Journal of Clinical Medicine. 2024;13(19):5940. doi:10.3390/jcm13195940.

36. Zhatkina MV, Gavrilova NE, Metelskaya VA, et al. Visual Scale as a Non-Invasive Method for Evaluation of Risk and Severity of Coronary Atherosclerosis. Kardiologiia. 2021;61(4):46-52. (In Russ.) doi:10.18087/cardio.2021.4.n1481.

37. Pereverzeva KG, Yakushin SS, Dubova NV. Electrocardiographic criteria for occlusive and prognostically unfavorable coronary artery disease. Russian Journal of Cardiology. 2024;29(3S):5699. (In Russ.) doi:10.15829/1560-4071-2024-5699.

38. Tsivanyuk MM, Geltser BI, Shakhgeldyan KI, et al. Parameters of complete blood count, lipid profile and their ratios in predicting obstructive coronary artery disease in patients with non-ST elevation acute coronary syndrome. Russian Journal of Cardiology. 2022;27(8):5079. (In Russ.) doi:10.15829/1560-4071-2022-5079.

39. Abdualimov TP, Obrezan AG. Detection of coronary artery disease using deep learning algorithms. Kardiologiya: novosti, mneniya, obuchenie. 2021;9(2):9-13. (In Russ.) doi:10.33029/2309-1908-2021-9-2-9-13.

40. Tsivanyuk MM, Geltser BI, Shakhgeldyan KI, et al. Electrocardiographic, echocardio­graphic and lipid parameters in predicting obstructive coronary artery disease in pa­ti­ents with non-ST elevation acute coronary syndrome. Russian Journal of Cardiology. 2022;27(6):5036. (In Russ.) doi:10.15829/1560-4071-2022-5036.


Supplementary files

  • Modern imaging methods allow to detect acute thrombosis of the infarct-­related artery in patients with non-­ST-elevation acute coronary syndrome.
  • Improvement of thrombosis diagnosis methods allows to improve the quality of healthcare for cardiovascular patients.
  • Systematization of literature data on the applied imaging methods of acute thrombosis of the infarct-­related artery in patients with non-­ST-elevation acute coronary syndrome.

Review

For citations:


Strelkova A.V., Chashchin M.G., Gorshkov A.Yu., Drapkina O.M., Yurin A.V., Gagarina E.V., Tereshchenko A.S. Modern features of coronary thrombosis imaging in non-ST-elevation acute coronary syndrome. Russian Journal of Cardiology. 2025;30(6S):6298. (In Russ.) https://doi.org/10.15829/1560-4071-2025-6298. EDN: NXMUNZ

Views: 133


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1560-4071 (Print)
ISSN 2618-7620 (Online)