Does clinical and scientific practice require blood pressure load indices from ambulatory monitoring: a scoping review
https://doi.org/10.15829/1560-4071-2025-6096
EDN: PJMOAU
Abstract
The aim of this review was to answer the question of whether clinical and research practice require blood pressure load indices from ambulatory BP monitoring data.
To identify related publications, a search of Pubmed, eLibrary, elpub databases and snowball sampling were used. A total of 264 publications were found. Then, publications were excluded in which the term "blood pressure load" stayed out of the context of 24-hour BP monitoring, as well as reviews and studies with fewer than 21 observations. A total of 69 publications selected were classified as follows: outcome studies; studies on target organ damage and risk factors; studies in special groups; intervention studies.
The literature review showed that there are no studies with methodology provided evidence of a clear additional value of BP load compared to mean BP values. In contrast, studies with high statistical power specifically aimed at the question under study showed lack of predictive power of BP loads for either outcome or target organ damage in general and special populations. There is also no evidence that any intervention based on target BP loads is superior to treatment based on standard BP. The results of our review suggest that there is no need to calculate BP loads. Routine clinical decision-making should be based only on standard BP values compared with the thresholds adopted by medical scientific societies in clinical guidelines.
About the Authors
I. N. Posokhov
Burnazyan Federal Medical Biophysical Center
Russian Federation
Competing Interests:
Russian Federation
ScD, Professor of the Department of Therapy of Burnazyan Federal Medical Biophysical Center; Visiting professor of West Kazakhstan Marat Ospanov Medical University.
Moscow
Competing Interests:
none
E. A. Praskurnichiy
Burnazyan Federal Medical Biophysical Center
Russian Federation
Competing Interests:
Russian Federation
ScD, Professor, Head of the Department of Therapy of Burnazyan Federal Medical Biophysical Center; Head of the Department of Therapy of Biomedicine Faculty of Pirogov Russian National Research Medical University.
Moscow
Competing Interests:
none
E. I. Zheleznyak
Rostov State Medical University
Russian Federation
Competing Interests:
Russian Federation
PhD, assistant. Department of Internal medicine N 2.
Rostov-on-Don
Competing Interests:
none
E. A. Kartashova
Rostov State Medical University
Russian Federation
Competing Interests:
Russian Federation
PhD, assistant professor. Department of Internal medicine N 2.
Rostov-on-Don
Competing Interests:
none
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Supplementary files
- Automatic reports generated by ambulatory blood pressure monitoring devices still contain blood pressure load indices, which can potentially be used by doctors instead of standard blood pressure level to make unfounded clinical decisions.
- The studies available in the literature do not support the independence or superiority of blood pressure load indices over the mean 24-hour or mean day-time or night-time blood pressure; and those studies specifically asked about such superiority or independence give a negative answer to it.
- Based on the available literature data covered by this review, there is no justification for the treatment of hypertension based on the target blood pressure load values.
Review
For citations:
Posokhov I.N., Praskurnichiy E.A., Zheleznyak E.I., Kartashova E.A. Does clinical and scientific practice require blood pressure load indices from ambulatory monitoring: a scoping review. Russian Journal of Cardiology. 2025;30(6S):6096. (In Russ.) https://doi.org/10.15829/1560-4071-2025-6096. EDN: PJMOAU
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