Myocardial infarction in persons aged ≥75 years: factors influencing inhospital mortality
https://doi.org/10.15829/1560-4071-2024-5629
EDN: ZSRZDJ
Abstract
Aim. To identify factors influencing inhospital mortality in patients with myocardial infarction aged ≥75.
Material and methods. We performed a retrospective analysis of medical records of all patients aged ≥75 years hospitalized from January 1, 2020 to December 31, 2021 with a diagnosis of myocardial infarction (I21, ICD-10), assessment of comorbidities, clinical performance, laboratory and treatment data and their impact on the outcome of hospitalization.
Results. Inhospital mortality was 22,2%. The mean age of discharged and deceased patients was 81 [79; 84] and 82 [79; 85] years, respectively (p=0,12). Cardiogenic shock on admission (hazard ratio (HR) 31,28; 95% confidence interval (CI) 5,7-171,53; p<0,001), degree 2-3 atrioventricular block (HR 4,67; 95% CI 1,02-21,38; p=0,04), as well as a GRACE score ≥166 for non-ST-segment elevation acute coronary syndrome (HR 7,19; 95% CI 1,01-51,43; p<0,001) showed an unfavorable effect on prognosis.
Conclusion. Cardiogenic shock, degree 2-3 atrioventricular block, and a GRACE score ≥166 for patients with non-ST-segment elevation acute coronary syndrome are factors that increase inhospital mortality in patients aged ≥75 years.
About the Authors
I. E. TishkinaRussian Federation
Ryazan
Competing Interests:
none
T. M. Kuleshova
Russian Federation
Ryazan
Competing Interests:
none
M. A. Frolova
Russian Federation
Moscow
Competing Interests:
none
K. G. Pereverzeva
Russian Federation
Ryazan
Competing Interests:
none
S. S. Yakushin
Russian Federation
Ryazan
Competing Interests:
none
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Supplementary files
- Issues of the effectiveness and safety of providing care to elderly patients with myocardial infarction (MI) require further study, since elderly patients are not sufficiently represented in clinical and registry studies on providing care to patients with MI.
- Medical records of patients aged ≥75 years with MI were analyzed and factors influencing inhospital mortality were identified.
- Poor prognostic factors in people aged ≥75 years include cardiogenic shock, degree 2-3 atrioventricular block, GRACE score ≥166 for patients with non-ST-segment elevation acute coronary syndrome.
Review
For citations:
Tishkina I.E., Kuleshova T.M., Frolova M.A., Pereverzeva K.G., Yakushin S.S. Myocardial infarction in persons aged ≥75 years: factors influencing inhospital mortality. Russian Journal of Cardiology. 2024;29(3):5629. (In Russ.) https://doi.org/10.15829/1560-4071-2024-5629. EDN: ZSRZDJ