Pleiotropic effect of the ABCA1 rs2230806 polymorphism in cardiovascular diseases: a literature review
https://doi.org/10.15829/1560-4071-2022-5127
Abstract
Cerebrovascular accident (CVA) in patients with various cardiovascular diseases is a life-threatening complication, the development of which can be contributed by both environmental and genetic factors, the understanding of which is necessary to determine the tactics of treatment and predict the disease course. The article presents a brief review of studies on genetic predictors of CVA, in particular the association of the ABCA1 rs2230806 polymorphism and the risk of CVA in cardiovascular patients. Targeted studies of associations of the ABCA1 rs2230806 polymorphism with cerebrovascular diseases in the Russian Federation, except for studies at our university, could not be found.
About the Authors
A. A. Chernova
V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University;
Federal Siberian Research Clinical Center
Russian Federation
Russian Federation
Anna A. Chernova
Krasnoyarsk
D. A. Nikulin
V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University;
Federal Siberian Research Clinical Center
Dmitriy A. Nikulin
Krasnoyarsk
S. Yu. Nikulina
V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University
Svetlana Yu. Nikulina
Krasnoyarsk
V. N. Maksimov
Research Institute of Internal and Preventive Medicine — a branch of the Federal Research Center Institute of Cytology and Genetics
Vladimir N. Maksimov
Laboratory of Molecular Genetic
Novosibirsk
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Supplementary files
Review
For citations:
Chernova A.A., Nikulin D.A., Nikulina S.Yu., Maksimov V.N. Pleiotropic effect of the ABCA1 rs2230806 polymorphism in cardiovascular diseases: a literature review. Russian Journal of Cardiology. 2022;27(10):5127. (In Russ.) https://doi.org/10.15829/1560-4071-2022-5127
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