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Эффекты применения ингибитора натрий-глюкозного котранспортера 2 типа дапаглифлозина у пациентов с сердечной недостаточностью с низкой фракцией выброса левого желудочка

https://doi.org/10.15829/1560-4071-2020-4049

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Аннотация

Ингибиторы натрий-глюкозного котранспортера 2 типа продемонстрировали способность снижать риск сердечно-сосудистых событий, развития и декомпенсаций сердечной недостаточности (СН) у пациентов с сахарным диабетом 2 типа (СД2). Улучшение прогноза СН может быть обусловлено не только сахароснижающим эффектом этого класса препаратов. В исследовании DAPA-HF у пациентов с СН с низкой фракцией выброса было продемонстрировано преимущество дапаглифлозина в снижении частоты сердечно-сосудистой смерти, ухудшения течения СН, улучшение симптомов СН по сравнению с плацебо, независимо от наличия СД2 и проводимой рекомендованной базовой терапии СН.

Об авторе

Н. Р. Хасанов
ФГБОУ ВО Казанский ГМУ Минздрава России
Россия

д. м.н., профессор, зав. кафедрой пропедевтики внутренних болезней

Казань



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Для цитирования:


Хасанов Н.Р. Эффекты применения ингибитора натрий-глюкозного котранспортера 2 типа дапаглифлозина у пациентов с сердечной недостаточностью с низкой фракцией выброса левого желудочка. Российский кардиологический журнал. 2020;25(8):4049. https://doi.org/10.15829/1560-4071-2020-4049

For citation:


Khasanov N.R. Effects of SGLT2 inhibitor dapagliflozin in patients with heart failure with reduced ejection fraction. Russian Journal of Cardiology. 2020;25(8):4049. (In Russ.) https://doi.org/10.15829/1560-4071-2020-4049

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ISSN 1560-4071 (Print)
ISSN 2618-7620 (Online)