ВЫБОР ФИКСИРОВАННЫХ КОМБИНАЦИЙ АНТИГИПЕРТЕНЗИВНЫХ ПРЕПАРАТОВ С ПОЗИЦИИ ОРГАНОПРОТЕКЦИИ
https://doi.org/10.15829/1560-4071-2015-5-127-133
Аннотация
В статье рассмотрены вопроса выбора комбинаций антигипертензивных препаратов с учетом их органо-протективных свойств. Подчеркивается, что поражение органов-мишеней (микроальбуминурия, повышение скорости пульсовой волны, гипертрофия миокарда левого желудочка, наличие атеросклеротических бляшек в сонных артериях, являются независимыми предикторами сердечнососудистой смертности. Рассмотрены наиболее оптимальные комбинации антигипертензивных средств при наличии поражения почек, сосудистой стенки, сердца и головного мозга. Приведены данные об органопротективных свойствах лерканидипина, эналаприла и их фиксированной комбинации.
Об авторах
О. Д. Остроумова
МГМСУ им. А.И.Евдокимова, Москва; Первый МГМУ им. И.М.Сеченова, Москва, Россия.
Россия
профессор, д.м.н., профессор кафедры факультетской терапии и профболезней, профессор кафедры клинической фармакологии и пропедевтики внутренних болезней
Россия
профессор, д.м.н., профессор кафедры факультетской терапии и профболезней, профессор кафедры клинической фармакологии и пропедевтики внутренних болезней
И. И. Копченов
МГМСУ им. А.И.Евдокимова, Москва
Россия
к.м.н., доцент кафедры факультетской терапии и профболезней
Россия
к.м.н., доцент кафедры факультетской терапии и профболезней
О. В. Бондарец
МГМСУ им. А.И.Евдокимова, Москва
Россия
к.м.н., доцент кафедры факультетской терапии и профболезней
Россия
к.м.н., доцент кафедры факультетской терапии и профболезней
Т. Ф. Гусева
МГМСУ им. А.И.Евдокимова, Москва
Россия
Россия
к.м.н., доцент кафедры факультетской терапии и профболезней
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Рецензия
Для цитирования:
Остроумова О.Д., Копченов И.И., Бондарец О.В., Гусева Т.Ф. ВЫБОР ФИКСИРОВАННЫХ КОМБИНАЦИЙ АНТИГИПЕРТЕНЗИВНЫХ ПРЕПАРАТОВ С ПОЗИЦИИ ОРГАНОПРОТЕКЦИИ. Российский кардиологический журнал. 2015;(5):127-133. https://doi.org/10.15829/1560-4071-2015-5-127-133
For citation:
Ostroumova O.D., Kopchenov I.I., Bondarets O.V., Guseva T.F. FIXED ANTIHYPERTENSIVE DRUGS COMBINATION SELECTION WITH THE AIM OF ORGANS PROTECTION. Russian Journal of Cardiology. 2015;(5):127-133. (In Russ.) https://doi.org/10.15829/1560-4071-2015-5-127-133
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