The role of calcium metabolism dysregulation in the pathogenesis of cardiovascular diseases
https://doi.org/10.15829/1560-4071-2019-9-78-85
Abstract
The review presents data on the causes of dysregulation of calcium metabolism and its association with the main elements of the cardiovascular continuum. Particular attention was paid to its role in the regulation of endothelial function, systemic inflammation, myocardial contractility, lipid and carbohydrate metabolism, the disruption of which determines the initiation and progression of diseases such as essential hypertension and chronic heart failure. We also systematized data on the role and methods of calcium dysmetabolism correcting in the prevention and treatment of these pathologies.
About the Authors
D. E. Mailian
M. Gorky Donetsk National Medical University
Ukraine
Donetsk
Competing Interests: Конфликт интересов не заявлен.
Ukraine
Donetsk
Competing Interests: Конфликт интересов не заявлен.
V. V. Kolomiets
M. Gorky Donetsk National Medical University
Ukraine
Donetsk
Competing Interests: Конфликт интересов не заявлен.
Ukraine
Donetsk
Competing Interests: Конфликт интересов не заявлен.
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Review
For citations:
Mailian D.E., Kolomiets V.V. The role of calcium metabolism dysregulation in the pathogenesis of cardiovascular diseases. Russian Journal of Cardiology. 2019;(9):78-85. (In Russ.) https://doi.org/10.15829/1560-4071-2019-9-78-85
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