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Features of chronic heart failure depending on the left ventricular ejection fraction

https://doi.org/10.15829/1560-4071-2019-2-7-11

Abstract

Aim. To assess clinical and demographic data, structural and functional features of the myocardium in patients with chronic heart failure (CHF) with a preserved ejection fraction in comparison with patients with CHF with an intermediate (CHF-inEF) and a reduced ejection fraction (CHF-rEF).

Material and methods. The study included 186 patients with CHF I-IIB stages, I-III functional classes. One hundred and three patients had a preserved ejection fraction (EF) (≥50%), 43 — intermediate (40-49%) and 40 — reduced (<40%). All patients underwent a comprehensive clinical examination, as well as standard echocardiography.

Results. Among patients with CHF-rEF, remodeling of the left ventricular myocardium by the type of concentric hypertrophy was more often observed (69,9%), and among CHF-inEF and CHF-nEF patients — by the type of eccentric hypertrophy (88,4 and 875%, respectively). Restrictive diastolic dysfunction was observed in 2,0% of patients with CHF-rEF and in 21,7% of patients with EF less than 50%.

Conclusion. The severity of the clinical course of CHF does not depend on the left ventricular EF. Epidemiology and etiology of CHF-rEF has fundamental differences from CHF-inEF and CHF-nEF: CHF-rEF is more common among women over 60 years old with arterial hypertension and obesity. For patients with CHF-inFV, myocardial remodeling by the type of concentric hypertrophy and the prevalence of non-restrictive types of diastolic dysfunction are characteristic.

About the Authors

A. G. Dushina
Orenburg State Medical University
Russian Federation

Competing Interests: nothing to declare


E. A. Lopina
Orenburg State Medical University
Russian Federation

Competing Interests: nothing to declare


R. A. Libis
Orenburg State Medical University
Russian Federation

Competing Interests: nothing to declare


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Review

For citations:


Dushina A.G., Lopina E.A., Libis R.A. Features of chronic heart failure depending on the left ventricular ejection fraction. Russian Journal of Cardiology. 2019;(2):7-11. https://doi.org/10.15829/1560-4071-2019-2-7-11

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ISSN 1560-4071 (Print)
ISSN 2618-7620 (Online)