THE ROLE OF PULSE REDUCTION THERAPY IN ADDITIONAL IMPROVEMENT OF CLINICAL EFFECTS OF MYOCARDIAL REVASCULARIZATION IN CORONARY HEART DISEASE STABLE ANGINA PATIENTS
https://doi.org/10.15829/1560-4071-2018-5-87-96
Abstract
The review is focused on the role of ivabradine in percutaneous coronary intervention (PCI) and coronary bypass grafting (CBG) in coronary heart disease patients (CHD) with stable angina. The data provided, on insufficient clinical effect of PCI revascularization with modern medication therapy. Authors argue for improvement of the clinical effect of PCI and CBG by addition of ivabradine together with sufficient (up to maximal) dosages of beta-adrenoblockers (BAB). Inhibition of If-channels of cardiomyocytes with ivabradine makes positive influence on the main clinical endpoints. The role of multiple effect of ivabradine is highlighted, that increase efficacy of the drug.
About the Authors
D. M. Aronov
National Research Center for Preventive Medicine of the Ministry of Health
Russian Federation
Moscow
Russian Federation
Moscow
M. G. Bubnova
National Research Center for Preventive Medicine of the Ministry of Health
Russian Federation
Moscow
Russian Federation
Moscow
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Review
For citations:
Aronov D.M., Bubnova M.G. THE ROLE OF PULSE REDUCTION THERAPY IN ADDITIONAL IMPROVEMENT OF CLINICAL EFFECTS OF MYOCARDIAL REVASCULARIZATION IN CORONARY HEART DISEASE STABLE ANGINA PATIENTS. Russian Journal of Cardiology. 2018;(5):87-96. (In Russ.) https://doi.org/10.15829/1560-4071-2018-5-87-96
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