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КАТЕСТАТИН КАК НОВЫЙ МАРКЕР СЕРДЕЧНО-СОСУДИСТОГО РИСКА У БОЛЬНЫХ  ГИПЕРТОНИЧЕСКОЙ БОЛЕЗНЬЮ

https://doi.org/10.15829/1560-4071-2018-4-111-116

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Аннотация

Обзор ключевых исследований по изучению антигипертензивного, вазодилататорного, ангиогенного и анти-апоптотического действия катестатина — пептида, образующегося в результате взаимодействия эндогенных протеаз с С-концом хромогранина А. Плазменные уровни катестатина обратно коррелируют с фенотипом артериальной гипертензии, особенно на ранних стадиях развития гипертонической болезни. Обсуждается патогенетическая роль катестатина в развитии гипертонической болезни и его возможное использование в качестве маркера стратификации сердечно-сосудистого риска.

Об авторах

Е. Ю. Губарева
ФГБОУ ВО Самарский государственный медицинский университет Минздрава России.
Россия

 очный аспирант кафедры внутренних болезней.

Самара.



Н. Н. Крюков
ФГБОУ ВО Самарский государственный медицинский университет Минздрава России.
Россия

профессор зав. кафедрой внутренних болезней, заслуженный деятель науки РФ.

Самара.

 



И. В. Губарева
ФГБОУ ВО Самарский государственный медицинский университет Минздрава России.
Россия
д. м.н., доцент кафедры внутренних болезней.


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Для цитирования:


Губарева Е.Ю., Крюков Н.Н., Губарева И.В. КАТЕСТАТИН КАК НОВЫЙ МАРКЕР СЕРДЕЧНО-СОСУДИСТОГО РИСКА У БОЛЬНЫХ  ГИПЕРТОНИЧЕСКОЙ БОЛЕЗНЬЮ. Российский кардиологический журнал. 2018;(4):111-116. https://doi.org/10.15829/1560-4071-2018-4-111-116

For citation:


Gubareva E.Y., Kryukov N.N., Gubareva I.V. CATESTATIN AS A NOVEL MARKER OF CARDIOVASCULAR RISK IN SYSTEMIC HYPERTENSION. Russian Journal of Cardiology. 2018;(4):111-116. (In Russ.) https://doi.org/10.15829/1560-4071-2018-4-111-116

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