Enalapril microhemodynamic effects in patients with essential arterial hypertension
Abstract
The study included 38 patients with essential arterial hypertension (EAH), Stage I-II, and 10 healthy individuals (control group). Microcirculation was assessed by laser Doppler flowmetry (IDF), endothelin-1 concentration - by immunoenzyme assay. In EAH patients, microcirculation was heterogeneous, with the prevalence of pathological static type. Enalapril was an effective and safe antihypertensive medication, beneficial for microcirculation system. Serum endothelin-1 concentration correlated with systolic blood pressure (BP), as well as with IDF endothelial activity.
About the Authors
L. N. Eliseeva
Кубанская государственная медицинская академия
Russian Federation
Russian Federation
Z. A. Baste
Кубанская государственная медицинская академия
Russian Federation
Russian Federation
S. P. Oransky
Кубанская государственная медицинская академия
Russian Federation
Russian Federation
A. Yu. Blednova
Кубанская государственная медицинская академия
Russian Federation
Russian Federation
Z. A. Avakimyan
Кубанская государственная медицинская академия
Russian Federation
Russian Federation
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Review
For citations:
Eliseeva L.N., Baste Z.A., Oransky S.P., Blednova A.Yu., Avakimyan Z.A. Enalapril microhemodynamic effects in patients with essential arterial hypertension. Russian Journal of Cardiology. 2005;(5):60-63. (In Russ.)
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