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Hyperhomocysteinemia in men population of Novosibirsk

Abstract

In population to the Siberian sample of men the prevalence of hyperhomocysteinemia (HHC) in winter-spring and in autumn seasons of year for the first time is studied, search of theoretically expected associations with CHD and with major factors of its risk is lead. It is executed a screening examination of representative sample of 243 men of 45-69 years with use of the standardized epidemiological and biochemical methods. The prevalence of HHC during the winter-spring period of year has made 43 %, during an autumn season of year has made 52 %. Statistically significant distinctions in the prevalence of HHC between seasons of year it is not revealed. It is not revealed correlation communications between a level of homocysteine blood and presence CHD. Positive correlation of homocysteinemia with the years, with a level of products of lipid peroxidation in IDI, and also its negative correlation with α-tocopherol level in LDL and with an index of weight of a body.

About the Authors

Yu. P. Nikitin
Научно-исследовательский институт терапии СО РАМН
Russian Federation


O. V. Motina
Научно-исследовательский институт терапии СО РАМН
Russian Federation


Yu. I. Ragino
Научно-исследовательский институт терапии СО РАМН
Russian Federation


G. I. Simonova
Научно-исследовательский институт терапии СО РАМН
Russian Federation


Ya. V. Polonskaya
Научно-исследовательский институт терапии СО РАМН
Russian Federation


M. V. Ivanova
Научно-исследовательский институт терапии СО РАМН
Russian Federation


L. V. Cherbakova
Научно-исследовательский институт терапии СО РАМН
Russian Federation


S. K. Malyutina
Научно-исследовательский институт терапии СО РАМН
Russian Federation


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For citations:


Nikitin Yu.P., Motina O.V., Ragino Yu.I., Simonova G.I., Polonskaya Ya.V., Ivanova M.V., Cherbakova L.V., Malyutina S.K. Hyperhomocysteinemia in men population of Novosibirsk. Russian Journal of Cardiology. 2007;(4):63-68. (In Russ.)

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ISSN 1560-4071 (Print)
ISSN 2618-7620 (Online)