HEART AND VESSELS INVOLVEMENT IN THE ANTIPHOSPHOLIPID SYNDROME
Abstract
An investigation was made into the clinical features of cardiac-vascular system of 200 patients with antiphospholipid syndrome (APS): 61 patients had PAPS (primary APS), 139 patients had SAPS (secondary APS), associated with systemic lupus erythematosus (SLE) (115 cases) or Sharp syndrome (24 cases). The data obtained indicate certain differences between PAPS and SAPS. Cardiac valve alteration, mainly of mitral valve, with either or insufficiency, stenosis, fibrosis, calcinosis and vegetations were suggestive of PAPS. SAPS was featured by more rare cardiac valve alterations (concerning mainly mitral valve); and arterial hypertension (50 per cent cases) of, probably, renal origin, which caused cardiomyopathy. These results may regard as differential-diagnostic criteria in clinical practice.
About the Authors
N. N. ChapayevaRussian Federation
A. A. Demin
Russian Federation
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Review
For citations:
Chapayeva N.N., Demin A.A. HEART AND VESSELS INVOLVEMENT IN THE ANTIPHOSPHOLIPID SYNDROME. Russian Journal of Cardiology. 2001;(3):25-28. (In Russ.)