CONCENTRIC MYOCARDIAL REMODELING IN CHRONIC RENAL FAILURE
Abstract
Increased LV myocardial mass (LVM) and alteration of its geometric model further cardiovascular risk and deteriorate prognosis in chronic renal failure (CRF).
The aim of the study was to observe the fine mechanism of early myocardial remodeling on various stages of CRF. The study included 106 patients aged 44,9±13,6 with non-diabetic CRF (74 pre-dialysis and 32 with dialysis-stage CRF) and normal LVM. Concentric myocardial remodeling (C-remodeling) was established with echocardiography with normal LVM and increased relative width of LCV walls. C-remodeling accounted for 36,7% cases in pre-dialysis and 63.3% in dialysisstage CRF. The risk factors for C-remodeling were: age, female sex with no physiological nocturnal fall in blood pressure, anemia, a more severe renal function impairment, a longer history of arterial hypertension, systolic and diastolic arterial hypertension. A greater mass increase between dialysis sessions was observed in patients with dialysis-stage CRF as compared to those with normal LV geometry.
About the Authors
G. V. Volgina
Московский государственный медико-профилактический университет
Russian Federation
Russian Federation
V. A. Dudayev
Московский государственный медико-профилактический университет
Russian Federation
Russian Federation
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Review
For citations:
Volgina G.V., Dudayev V.A. CONCENTRIC MYOCARDIAL REMODELING IN CHRONIC RENAL FAILURE. Russian Journal of Cardiology. 2001;(5):21-25. (In Russ.)
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