Predicting hypotensive effect of physical training in arterial hypertension patients

Abstract

The aim of the study was to identify predictors of physical training (PT) hypotensive effects inpatients with Stage I-II arterial hypertension (AH). In total, 74 patients were examined. In 35 (47 %), substantial hypotensive PT effect was registered, and in other 39 (53 %), it was not observed (Group II). At baseline, in Group I, higher mean diastolic and mean hemodynamic blood pressure (BP), pressure load indices, as well as more manifested left ventricular (IV) diastolic dysfunction, and cerebral blood flow auto-regulation disturbance, taking into account metabolic and myogenic reserve ratio, were observed. In Group II, with inadequate hypotensive PT effect, middle cerebral artery (MCA) area resistance was more increased. Similar results were obtained while developing a diagnostic scale. Therefore, hypotensive PT effect predictors were AH severity, IV diastolic dysfunction, unchanged MCA peripheral resistance indices, and decreased metabolic reserve of cerebral blood flow auto-regulation.