Preview

Russian Journal of Cardiology

Advanced search

Calcificated degenerative aortal stenosis: clinical and instrumental parameters

Abstract

The article is devoted to complex assessment of several clinical and instrumental parameters inpatients with calcificated degenerative aortal stenosis (CDAS) of varying severity. The main group included 101CDAS patients, the control group - 32 individuals with coronary heart disease (CHD)) and / or arterial hypertension, but without aortal valve pathology, according to echocardiography data. Aortal stenosis progression was associated with increased prevalence of angina pain syndrome, paroxysmal night dyspnoe, vertigo, atypical systolic murmur, and aortal regurgitation. Hotter monitoring demonstrated myocardial ischemia in 32, 6 % of CDAS patients, and stair test - in 66, 6 % (painless ischemia in 57, 6 % of the cases). Physical stress tolerance decreased as aortal stenosis severity increased.

About the Authors

N. A. Shostak
Российский государственный медицинский университет
Russian Federation


N. Yu. Karpova
Российский государственный медицинский университет
Russian Federation


M. A. Rashid
Российский государственный медицинский университет
Russian Federation


D. V. Piskunov
Российский государственный медицинский университет
Russian Federation


M. E. Yadrov
Российский государственный медицинский университет
Russian Federation


References

1. ACC/AHA guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients with Valvular Heart Disease)//J. Am. Coll. Cardiol. 1998. N 32. P. 1486-1588.

2. Anderson R.H., Devine W.A., Ho S.Y., et al. The myth of the aortic annulus: the anatomy of the subaortic outflow trac. // Ann. Thorac. Surg. 1991. N 51. P. 640-664.

3. Antonini-Canterin E., Huang G., et al. Symptomatic aortic stenosis. Does systemic hypertension play an additional role? // Hypertension. 2003. N 41. P. 1268-1272

4. Braunwald E. On the natural history of severe aortic stenosis [editorial]//J. Am. Coll. Cardiol. 1990. N 15. P. 1018-1020.

5. Carabello B. Aortic stenosis.//N. Engl. J. Med. 2002. Vol. 346, N 9. P. 677-682.

6. ESC working group report. Recommendations on the management of the asymptomatic patient with valvular heart disease // Eur. Heart J. 2002. Vol. 23, N 16. P. 1253-1266.

7. Otto С.М., Aikawa K. Timing of surgery in aortic stenosis//Progress in cardiovascular diseases. 2001. Vol. 43, N 6. P. 477-493.

8. Pellica P.A., Sarano M.E., Nishimura R.A., et al. Outcome of 622 adults with asymptomatic, hemodynamically significant aortic stenosis during prolonged follow-up//Circulation. 2005. N 111. P. 3290-3295.

9. Rahimtoola S.H. Severe aortic stenosis with low systolic gradient. The good and bad news // Circulation. 2000. N 101. P. 1892-1894.

10. Rajamannan N., Gersh В., Bonow R.O. Calcific aortic stenosis: from bench to the bedside -emerging clinical and cellular concepts//Heart. 2003. N 89. P. 801-805.

11. Rosenhek R. Statins for aortic stenosis//N. Engl. J. Med. 2005. N 352. P. 2441-2443.

12. Tenenbaum A., Fisman E., Schwammenthal E., et al. Aortic valve calcification in hypertensive patients: prevalent risk factors and association with transvalvular flow velocity.//Int. J. Cardiol. 2004. N 94 (1). P. 7-13.


Review

For citations:


Shostak N.A., Karpova N.Yu., Rashid M.A., Piskunov D.V., Yadrov M.E. Calcificated degenerative aortal stenosis: clinical and instrumental parameters. Russian Journal of Cardiology. 2006;(5):40-44. (In Russ.)

Views: 826


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1560-4071 (Print)
ISSN 2618-7620 (Online)