STRUCTURE OF COGNITIVE DISORDERS AND DYNAMICS OF BIOELECTRIC ACTIVITY OF THE BRAIN IN PATIENTS AFTER DIRECT MYOCARDIAL REVASCULARIZATION
Abstract
Aim. To analyze structural chareacteristics and electroencephalographic (EEG) pattern of post-operation cognitive dysfunction (POCD) in patients after direct myocardial revascularization under artificial circulation (AI). Material and methods. Totally 114 male-patients included, underwent scheduled coronary bypass grafting (CBG) under the AI, with average age 55,9±5,3 y. In 3-5 days before operation and on 7-10 day after all patients underwent neurophysiological testing; of those 65 patients also underwent EEG. Results. The CBG operation with AI leads in 79% of cases to the early POCD. Cognitive impairment usually becomes prominent in the domains of neurodynamics and memory. It is shown that the early POCD is followed by EEG-signs of cortical dysfunction (increase of low-frequency theta-rhythm magnitude).
Conclusion. According to the results of the study, in post-operative CBG with AI period the structure of POCD consists of injury of neurodynamics and memory, which might be a cause of decreased life quality of patients and efficacy of surgery itself.
About the Authors
O. A. Trubnikova
FSBU SPI of the Complex Cardiovascular Disorders of SI RAMS, Kemerovo, Russia.
Russian Federation
Russian Federation
I. V. Tarasova
FSBU SPI of the Complex Cardiovascular Disorders of SI RAMS, Kemerovo, Russia.
Russian Federation
Russian Federation
A. S. Mamontova
FSBU SPI of the Complex Cardiovascular Disorders of SI RAMS, Kemerovo, Russia.
Russian Federation
Russian Federation
I. D. Syrova
FSBU SPI of the Complex Cardiovascular Disorders of SI RAMS, Kemerovo, Russia.
Russian Federation
Russian Federation
O. V. Maleva
FSBU SPI of the Complex Cardiovascular Disorders of SI RAMS, Kemerovo, Russia.
Russian Federation
Russian Federation
O. L. Barbarash
FSBU SPI of the Complex Cardiovascular Disorders of SI RAMS, Kemerovo, Russia.
Russian Federation
Russian Federation
References
1. Bokerija LA, Goluhova EZ, Polunina AG, et al. Cognitive function after surgery with extracorporeal circulation in the early and late postoperative period. Kreativnaja kardiologija, 2011; 2: 71-88. Russian (Бокерия Л. А. Голухова Е. З., Полунина А. Г. и др. Когнитивные функции после операций с искусственным кровообращением в раннем и отдаленном послеоперационном периоде. Креативная кардиология, 2011; 2: 71-88).
2. Phillips-Bute B, Mathew JP, Blumenthal JA, et al. Association of neurocognitive function and quality of life 1 year after coronary artery bypass graft (CABG) surgery. Psychosomatic Medicine, 2006; 68: 369-75.
3. Kozora E, Kongs S, Collins JF, et al. Cognitive outcomes after on- versus off-pump coronary artery bypass surgery. Ann. Thorac. Surg. 2010; 90: 1134-41.
4. Siepe M, Pfeiffer T, Gieringer A, et al. Increased systemic perfusion pressure during cardiopulmonary bypass is associated with less early postoperative cognitive dysfunction and delirium. Eur J Cardiothorac Surg. 2011; 40 (1): 200-7.
5. Selnes OA, Grega MA, Bailey Maryanne M, et al. Neurocognitive outcomes 3 years after coronary artery bypass graft surgery: a controlled study. Ann Thorac Surg. 2007; 84: 1885-96.
6. Golukhova EZ, Polunina AG, Lefterova NP, et al. Electroencephalography as a tool for assessment of brain ischemic alterations after open heart operations. Stroke Res Treat. 2011;2011:980873.
7. Tarasova IV, Volf NV, Trubnikova OA, et al. EEG changes in patients undergoing coronary artery bypass surgery under extracorporeal circulation. Zhurnal nevrologii i psihiatrii im. C. C. Korsakova, 2012; 112 (3): 13-7. Russian (Тарасова И. В., Вольф Н. В., Трубникова О.А.и др. Изменения электроэнцефалограммы у пациентов, перенес¬ших коронарное шунтирование в условиях искусственного кровообращения. Журнал неврологии и психиатрии им. C. C. Корсакова. 2012; 112 (3): 13-7).
8. Silbert BS, Maruff P, Evered LA, et al. Detection of cognitive decline after coronary surgery: a comparison of computerized and conventional tests. Br J Anaesth. 2004; 92 (6): 814-20.
9. Dement'eva II, Morozov JuA, Sandrikov VA, et al. The problem of cerebral microembolic complications in cardiac surgery patients and rheological methods for their prevention. Patologija krovoobrashhenija i kardiohirurgija, 2010; 3: 50-5. Russian (Дементьева И. И., Морозов Ю. А., Сандриков В. А., и др. Проблема церебральных микроэмболических осложнений у кардиохирургических больных и гемореологические методы их профилактики. Патология кровообращения и кардиохирургия. 2010; 3: 50-5).
10. Raja SG, Berg GA. Impact of off-pump coronary artery bypass surgery on systemic inflammation: current best available evidence. J. Card. Surg. 2007; 22: 445-55.
11. van Harten E, Scheeren TWL, Absalom AR. A review of postoperative cognitive dysfunction and neuroinflammation associated with cardiac surgery and anaesthesia. Anaesthesia 2012;66:280-93.
12. Valdueza JM, Schreiber SJ, Roehl JE, et al. Neurosonology and Neuroimaging of Stroke. NY: Thieme Medical Publishers, Inc. 2008, 384 p.
13. Shmidt R, Tevs G. Human Physiology. 3th ed. Moscow: Mir; 2005; P.1, 323 p. Russian. (Шмидт Р., Тевс Г. Физиология человека. 3-е изд. М.: Мир; 2005; Т. 1, 323 с.).
14. Shnajder NA, Salmina AB. Neurological complications of general anesthesia. 2th ed. Moscow: Medika; 2009; 280 p. Russian. (Шнайдер Н. А., Салмина А. Б. Неврологические осложнения общей анестезии. 2-е издание. Москва: Медика; 2009; 280 с).
Review
For citations:
Trubnikova O.A., Tarasova I.V., Mamontova A.S., Syrova I.D., Maleva O.V., Barbarash O.L. STRUCTURE OF COGNITIVE DISORDERS AND DYNAMICS OF BIOELECTRIC ACTIVITY OF THE BRAIN IN PATIENTS AFTER DIRECT MYOCARDIAL REVASCULARIZATION. Russian Journal of Cardiology. 2014;(8):57-62. (In Russ.)
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