Effectiveness of preJhospital betaJblocker therapy in patients with acute coronary syndrome
Abstract
To assess the effectiveness of pre-hospital beta-blocker therapy in patients with acute coronary syndrome (ACS), 76 individuals with Q-wave myocardial infarction (Q-MI), and 62 persons with non-Q wave MI (non-Q-MI) were examined. Q-IM patients received aspirin, streptokinase, heparin, beta-blocker, and enalapril. They were divided into two groups, according to reperfusion status after thrombolysis (TL): Group I (reperfusion), Group II (no reperfusion). Each group was divided into subgroups, by the time of beta-blocker administration: subgroups Ia and IIa – pre-hospital administration, Ib and IIb – hospital treatment. Patients with non-Q-IM (Group III) were also divided into subgroups: IIIa – pre-hospital beta-blocker administration, IIIb – hospital beta-blocker treatment. Early (pre-hospital) beta-blocker therapy was associated with reduced area of myocardial necrosis, improved systolic and diastolic function, left ventricular geometry and clinical prognosis in MI patients.
About the Authors
G. M. Baitova
Отделение ургентной кардиологии НЦКиТ имени академика М.Мирраxимова, Бишкек
Kyrgyzstan
Kyrgyzstan
Y. M. Madyarova
Отделение ургентной кардиологии НЦКиТ имени академика М.Мирраxимова, Бишкек
Kyrgyzstan
Kyrgyzstan
M. T. Beyshenkulov
Отделение ургентной кардиологии НЦКиТ имени академика М.Мирраxимова, Бишкек
Kyrgyzstan
Kyrgyzstan
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Review
For citations:
Baitova G.M., Madyarova Y.M., Beyshenkulov M.T. Effectiveness of preJhospital betaJblocker therapy in patients with acute coronary syndrome. Russian Journal of Cardiology. 2008;(1):43-49. (In Russ.)
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