PREDICTORS OF CORONARY ARTERIES RESTENOSIS AFTER STENTING IN OBESE WOMEN
https://doi.org/10.15829/1560-4071-2014-9-31-36
Abstract
Aim. To study predictors of coronary arteries (CA) restenosis after stenting in women with coronary heart disease (CHD) and obesity.
Material and methods. Totally 57 women included (57,1±7,8 y.o.) with CHD: stable angina II-IV functional class and general obesity I-III grade (body mass index — BMI>30 kg/m2) (33,61±2,81 kg/m2), admitted for planned percutaneous intervention (PCI) with CA stenting. Prospective follow-up performed during 1 year after PCI. As resthenosis of CA we mentioned significant (>50%) narrowing of vessel lumen in the area of intervention. All patients underwent laboratory study with assessment of the main and additional metabolic risk factors and EchoCG with measurement of epicardial fat tissue (EFT) thickness.
Results. In 35% (n=19) patients the restenosis of CA revealed. The equation of logictic regression was formulated with the most important complex of predictors for resthenosis: the age (standardized regression coefficient SRC=0,7360), insulin (SRC=0,4821), and EFT (SRC=0,4224). The proportion of veritable prediction was 86,6%. The square under ROC-curve was 0,865.
Conclusion. The model had been developed may be useful in clinical practice to stratify the risk of complications before planned stenting of CA to improve secondary prevention of CHD.
About the Authors
N. G. Veselovskaya
FSBI SRI for Complex Problems of Cardiovascular Diseases of SD RAMS, Kemerovo
Altai Region Cardiological Dispensary, Barnaul, Russia
Russian Federation
Russian Federation
G. A. Chumakova
FSBI SRI for Complex Problems of Cardiovascular Diseases of SD RAMS, Kemerovo
Altai State Medical University, Barnaul
Russian Federation
Russian Federation
N. N. Shenina
Altai State Medical University, Barnaul
Russian Federation
Russian Federation
E. S. Osipova
Altai State Medical University, Barnaul
Altai Region Cardiological Dispensary, Barnaul, Russia
Russian Federation
Russian Federation
O. V. Gricenko
FSBI SRI for Complex Problems of Cardiovascular Diseases of SD RAMS, Kemerovo
Altai State Medical University, Barnaul
Russian Federation
Russian Federation
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Review
For citations:
Veselovskaya N.G., Chumakova G.A., Shenina N.N., Osipova E.S., Gricenko O.V. PREDICTORS OF CORONARY ARTERIES RESTENOSIS AFTER STENTING IN OBESE WOMEN. Russian Journal of Cardiology. 2014;(9):31-36. (In Russ.) https://doi.org/10.15829/1560-4071-2014-9-31-36
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