AGE AND GENDER SPECIFICS OF MYOCARDIAL REMODELLING IN PATIENTS ON PLANNED HEMODIALYSIS
Abstract
This study investigated the effects of hemodialysis, age, and gender on the development of various myocardial remodelling types. In total, 399 patients were examined: 184 on planned hemodialysis, 117 with pre-dialysis chronic kidney failure (CKF), and 98 with renal disease, but no CKF. All participants underwent standard clinical, laboratory, and instrumental tests. In both genders, the prevalence of pathological types of myocardial remodelling increased from CKF-free patients to patients with pre-dialysis CKF and to hemodialysis patients. Hemodialysis was associated with eccentric left ventricular hypertrophy (LVH), as one of the most adverse remodelling types, only in young women. The effects of age on structural myocardial remodelling differed by gender. In particular, among older hemodialysis patients, compared to their younger peers, concentric LVH was more prevalent in women, while concentric remodelling was more prevalent in men.
About the Authors
O. V. Rtishcheva
Челябинская областная клиническая больница; кафедра внутренних болезней и семейной медицины
Russian Federation
Russian Federation
O. F. Kalev
ГОУ ВПО Челябинская государственная медицинская академия Росздрава, Челябинск
Russian Federation
Russian Federation
References
1. Диагностика и лечение артериальной гипертензии. ВНОК. Национальные клинические рекомендации. Москва 2010. С. 20–56.
2. Ромашова Е. П., Давыдкин И. Л. Особенности ремоделирования левого желудочка у больных хронической почечной недосточностью, получающих лечение амбулаторным гемодиализом//Тер. архив, 2009. № 1, С. 21–24.
3. Delima J. J., Vieira M. L., Abensur H. et al. Baseline blood pressure and other variables influencing survival on hemodialysis of patients without overt cardiovascular disease//Nephrol. Dial. Transplant.2001; 16: 793–797.
4. Levin A., Singer J., Thompson C. R. et al. Pravalent left ventricular hypertrophy in the predialysis population: Idenufuing the opportunities for intervention//Am. J. Kidney Dis. 1996; 27: 347-354.
5. London G. M., Fabiani F. Left venricular dysfunction in end-stage renal disease: Echocardiographic insights. In: Parfrey P. S., Harnett J. D. eds Cardiac dysfunction in chronic uremia. Boston: Kluwer; 1992. 117-138.
6. Pleffer M. A. Left ventricular remodeling after acute myocardial infarction. Experimental observations and clinical implication//AR Medicine.–1995.–№ 46: 1161–1172.
7. Thuraisingham R. C., Tucker B., Lipkin G. W. et al. Left ventricular hypertrophy in early failure//Nephrol.Dial. Transplant. 1994; 7: 859-860.
8. Straumann E., Bartel O., Meyer B. et al. Symmetric and asymmetric left ventricular hypertrophy in patients with end -stage renal failure on longterm hemodialesis//Clin. Cardiol. 1998;21 (9):672–678.
9. Zoccalli C., Benedetto S. M., Mallamaci F. et al. Prognostic impact of the indexation of left ventricular mass in patients undergoing dialysis//Am. Soc. Nephrol.2001; 12: 2768–2774.
Review
For citations:
Rtishcheva O.V., Kalev O.F. AGE AND GENDER SPECIFICS OF MYOCARDIAL REMODELLING IN PATIENTS ON PLANNED HEMODIALYSIS. Russian Journal of Cardiology. 2011;(6):38-42. (In Russ.)
Views:
401
Email this article 