ASSOCIATION OF ELECTROCARDIOGRAPHIC MARKERS OF METABOLIC CARDIOMYOPATHY WITH LONG-TERM RESULTS OF MYOCARDIAL REVASCULARIZATION IN MEN WITH CORONARY ATHEROSCLEROSIS

Aim. To study electrocardiographic (ECG) markers of metabolic cardiomyopathy (MC) in men with coronary atherosclerosis (CA) in association with 5-year long-term results of coronary artery bypass grafting (CABG).

Material and methods. The study included 77 men aged 42-77 years with stenotic CA verified during selective coronary angiography (CAG) without acute coronary syndrome (ACS) and stable angina FC II-IV — the inhabitants of Western Siberia, admitted to the hospital for CABG. All patients before CABG underwent ECG at rest in 12 standard leads, followed by coding Minessota code. We analyzed ECG markers of MC, as the length of the interval QT, corrected interval QT, ST segment above the contour >5mm, ST segment depression below the contour >5mm non-ischemic type, T-wave changes (flattening or reduction of amplitude), the inversions, syndrome TV1>TV6 (amplitude of T in V1 exceeds the amplitude of T in V6), signs of left ventricular hypertrophy (LVH), arrhythmias and conduction disorder. Results. In men with CA before the CABG registered the following ECG markers MK: arrhythmias in 38 patients, LVH — in 55, the syndrome TV1>TV6 — in 24, the change of the T wave — in 58, segment ST elevation — in 44, segment ST depression — in 23, prolongation of the interval QT — in 5. The results were obtained in 5-year course of CA after surgical myocardial revascularization. The group of men with complicated CA (adverse long-term prognosis) was revealed. A positive correlation between the presence of the syndrome TV1>TV6 and fatal outcomes in the long term was found. The relative risk of death during 5-year period after CABG in patients with the syndrome TV1>TV6 was higher than in the group without the syndrome. In patients with the TV1>TV6 syndrome the relative risk of unfavourable later period as a whole (death, myocardial infarction, reoperation) was higher than of favourable. A positive correlations between ST-segment elevation before CABG and long term fatal outcomes, and in general, an unfavourable long term prognosis, were found. In patients with ST-segment elevation the relative risk of unfavourable later period is generally higher than of favourable. Conclusion. There is an association of electrocardiographic markers of MK (syndrome TV1>TV6, segment ST elevation) with 5-year long-term results of coronary revascularization in men with coronary atherosclerosis.

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