Left atrial appendage electrical isolation in the treatment of patients with atrial fibrillation: a literature review
https://doi.org/10.15829/1560-4071-2025-6651
EDN: XCROEB
Abstract
Catheter-based pulmonary vein isolation is the treatment of choice for patients with symptomatic atrial fibrillation (AF). Despite technological advances, the treatment efficacy, according to various sources, does not exceed 60-80%. In the vast majority of cases, this is due to nonpulmonary sources of arrhythmia. One of the most underestimated structures for the initiation and maintenance of AF is the left atrial appendage (LAA). This literature review provides a current understanding of LAA isolation methods, their effectiveness, and potential complications. It also addresses the issue of potential thromboembolic events after LAA isolation, which is the most common and significant limitation to the widespread use of procedure.
About the Authors
A. A. Brutyan
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation
Russian Federation
Petroverigsky Lane, 10, bld. 3, Moscow, 101990
K. V. Davtyan
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation
Russian Federation
Petroverigsky Lane, 10, bld. 3, Moscow, 101990
I. A. Chugunov
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation
Russian Federation
Petroverigsky Lane, 10, bld. 3, Moscow, 101990
G. Yu. Simonyan
National Medical Research Center for Therapy and Preventive Medicine
Russian Federation
Russian Federation
Petroverigsky Lane, 10, bld. 3, Moscow, 101990
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- Left atrial appendage electrical isolation is a safe adjunct to standard pulmonary vein isolation in patients with persistent atrial fibrillation.
- Patients after successful left atrial appendage electrical isolation require continuous anticoagulation or implantation of an occlusion device.
Review
For citations:
Brutyan A.A., Davtyan K.V., Chugunov I.A., Simonyan G.Yu. Left atrial appendage electrical isolation in the treatment of patients with atrial fibrillation: a literature review. Russian Journal of Cardiology. 2025;30(4S):6651. (In Russ.) https://doi.org/10.15829/1560-4071-2025-6651. EDN: XCROEB
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