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CORONARY ARTERY VASOSPASM SECONDARY TO TYPE I VARIANT KOUNIS SYNDROME: A CASE SERIES OF MEN. IS THE GENDER DIFFERENCES IMPORTANT?

https://doi.org/10.15829/1560-4071-2014-4-ENG-66-67

Abstract

Kounis syndrome is a well-known cause of acute coronary syndrome and more than 100 cases are reported with allergic reactions to various drugs, animal and insect bites, even with drug eluting stents and endovascular devices. In this paper we report five-patients with Kounis syndrome related to different drugs. The main characteristic of patients is given in Table 1. All of them were male and their age was from 18 to 35. All patients presented with ST- elevation myocardial infarction. Coronary angiography was performed in all patients and revealed normal coronary arteries. From history of allergic exposure, electrocardiographic, laboratory (Total IgE and tryptase levels) and angiographic findings the diagnosis was Kounis syndrome type I for all patients and was treated with oral antihistamines and prednisolone. Despite Type 1 KS is not associated with atherosclerotic risk factors and CAD all patients in or report and many patients in literature are male. Gender differences in KS should be investigated in further studies.

About the Authors

Cuneyt Kocas
Department of Cardiology, Istanbul University Cardiology Institute, Istanbul

MD, Istanbul University Institute of Cardiology, Department of Cardiology, Cardiologist, Instructor; Haseki, Aksaray 34350, Istanbul/Turkey, Tel: +90 505 938 35 27, Fax: +90 216 469 37 96



Ahmet Cagri Aykan
Department of Cardiology, Kartal Kosuyolu Educational and Reseach Hospital, Istanbul, Turkey


Okay Abaci
Department of Cardiology, Istanbul University Cardiology Institute, Istanbul


Gokhan Cetinkal
Department of Cardiology, Istanbul University Cardiology Institute, Istanbul


Sukru Arslan
Department of Cardiology, Istanbul University Cardiology Institute, Istanbul


Mustafa Yildiz
Department of Cardiology, Istanbul University Cardiology Institute, Istanbul


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Review

For citations:


Kocas C., Aykan A.C., Abaci O., Cetinkal G., Arslan S., Yildiz M. CORONARY ARTERY VASOSPASM SECONDARY TO TYPE I VARIANT KOUNIS SYNDROME: A CASE SERIES OF MEN. IS THE GENDER DIFFERENCES IMPORTANT? Russian Journal of Cardiology. 2014;(4-ENG):66-67. https://doi.org/10.15829/1560-4071-2014-4-ENG-66-67

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ISSN 1560-4071 (Print)
ISSN 2618-7620 (Online)