Myocardial infarction and pulmonary embolism in a young man during feminizing gender-affirming therapy: а case report
https://doi.org/10.15829/1560-4071-2025-6116
EDN: XHKQSO
Abstract
More than 100 million women use combined oral contraceptives to prevent unintended pregnancy, as well as for a number of other medical indications. Taking estrogen and progestin drugs is associated with the risk of acute thromboembolic and vascular events. This is a consequence of an increase in serum coagulation factors and a direct effect on endothelial dysfunction, which enhances platelet aggregation. This article demonstrates the development of myocardial infarction and pulmonary embolism in a young man during feminizing therapy.
About the Authors
D. A. Grabovyi
Polyakov Samara Regional Clinical Cardiology Dispensary
Russian Federation
Competing Interests:
Russian Federation
Samara
Competing Interests:
None
G. R. Bikbaeva
Polyakov Samara Regional Clinical Cardiology Dispensary
Russian Federation
Competing Interests:
Russian Federation
Samara
Competing Interests:
None
I. A. Osadchii
Polyakov Samara Regional Clinical Cardiology Dispensary
Russian Federation
Competing Interests:
Russian Federation
Samara
Competing Interests:
None
A. A. Tukhbatova
Polyakov Samara Regional Clinical Cardiology Dispensary
Russian Federation
Competing Interests:
Russian Federation
Samara
Competing Interests:
None
D. V. Duplyakov
Polyakov Samara Regional Clinical Cardiology Dispensary
Russian Federation
Competing Interests:
Russian Federation
Samara
Competing Interests:
None
References
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7. Gabelova KA, Shabanova NA, Bezhenar VF, et al. Risks of venous thromboembolic complications in related to combined oral contraceptives. Akusherstvo, Ginekologia i Reprodukcia = Obstetrics, Gynecology and Reproduction. 2021;15(6):777-87. (In Russ.)
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For citations:
Grabovyi D.A., Bikbaeva G.R., Osadchii I.A., Tukhbatova A.A., Duplyakov D.V. Myocardial infarction and pulmonary embolism in a young man during feminizing gender-affirming therapy: а case report. Russian Journal of Cardiology. 2025;30(5S):6116. (In Russ.) https://doi.org/10.15829/1560-4071-2025-6116. EDN: XHKQSO
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