CLINICAL OPINION: BRUGADA SYNDROME AND SICK SYNUS SYNDROME — CASE WHICH WE MEET IN OUR PRACTICE
https://doi.org/10.15829/1560-4071-2014-1-ENG-49-51
Abstract
In our work we describe the case of a patient with a Brugada syndrome. It is a rare syndrome which carries a potential risk of sudden cardiac death which occurs usually at an early age. Unfortunately it is most frequently the first clinical manifestation of this genetic disease. Sometimes, as in our patient it could co-exist with other cardiovascular abnormalities which give us an opportunity to establish the right diagnosis and apply adequate preventive measures. It is of paramount importance to explore the possibility of the existence of this syndrome in the patient’s family members. The first diagnostic procedure is an ECG which is an inexpensive and readily available diagnostic tool.
About the Authors
Tomislav Kostic
Clinic for cardiovascular diseases, Clinical Centre Nis, Nis
Zoran Perisic
Clinic for cardiovascular diseases, Clinical Centre Nis, Nis
Medical Faculty, University of Nis
Boris Djindjic
Clinic for cardiovascular diseases, Clinical Centre Nis, Nis
Medical Faculty, University of Nis
Goran Koracevic
Clinic for cardiovascular diseases, Clinical Centre Nis, Nis
Medical Faculty, University of Nis
Milan Zivkovic
Clinic for cardiovascular diseases, Clinical Centre Nis, Nis
Aleksandar Stojkovic
Clinic for cardiovascular diseases, Clinical Centre Nis, Nis
Dragana Stanojevic
Clinic for cardiovascular diseases, Clinical Centre Nis, Nis
Clinic for cardiovascular diseases, Clinical Centre Nis, Nis, Serbia; Bulevar Zorana Djindjića 48, 18000 Nis, Serbia, Tel:
+38 1643068447, Fax: +38 1184221674
Vladimir Mitov
Health Centre Zajecar, Zajecar, Serbia
References
1. Brugada P, Brugada J. Right bundle branch block, persistent ST segment elevation and sudden cardiac death: A distinct clinical and electrocardiographic syndrome. A multicenter report. J Am Coll Cardiol 1992; 20:1391–6.
2. Antzelevitch C, Brugada P, Borggrefe M et al. Brugada syndrome: Report of the Second Consensus Conference. Circulation 2005;111: 659–70.
3. Richter S, Sarkozy A, Chierchia GB, et al. Variability of the diagnostic coved type ECG during long term follow up of patients with Brugada syndrome and primary prophylactic ICD implantation. Eur Heart J 2008; 27 (S1).
4. Hong K, Brugada J, Oliva A, et al. Value of electrocardiographic parameters and ajmaline test in diagnosis of Brugada syndrome caused by SCN5A mutations. Circulation 2004;110: 3023–7.
5. Probst V, Allouis M, Sacher F, et al. Progresive cardiac conduction defect is the prevailing phenotype in cariers of a Brugada syndrome SCN5A mutation. J Cardiovasc Electrophysiol 2006;17: 270–5.
6. Coronel R, Casini S, Koopmann T, et al. Right ventricular fibrosis and conduction delay in a patients with clinical signs og Brugada syndrome. Circulation 2005;112: 2769–77.
7. Boussy T, Brugada R, Brugada J, et al. The Brugada Syndrome, In: Zippes, Jalife. Cardiac Electrophysiology, fifth edition. Saunders Elselvier 2009.
8. Hermida JS, Denjoy I, Clerc J, et al. Hydroquinidine therapy in Brugada syndrome. J Am Coll Cardiol 2004; 43: 1853–60.
9. Fish JM, Welchons DR, Kim Y, et al. Dimethyl lithospermate B, an extract of Danshen, suppresses arrhythmogenesis associated with Brugada syndrome. Circulation 2006;113: 1393–400.
Review
For citations:
Kostic T., Perisic Z., Djindjic B., Koracevic G., Zivkovic M., Stojkovic A., Stanojevic D., Mitov V. CLINICAL OPINION: BRUGADA SYNDROME AND SICK SYNUS SYNDROME — CASE WHICH WE MEET IN OUR PRACTICE. Russian Journal of Cardiology. 2014;(1-ENG):49-51. https://doi.org/10.15829/1560-4071-2014-1-ENG-49-51
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