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Systemic inflammatory response after transcatheter aortic valve replacement: a case report

https://doi.org/10.15829/15604071-2024-5936

EDN: TCTGNT

Abstract

Introduction. The growing prevalence of transcatheter aortic valve implantation (TAVI) over the past few years has revealed a unique set of events and complications that require rapid identification and treatment to improve outcomes, often involving a multidisciplinary team.

Brief description. We present the case of a 79-year-old woman with severe aortic stenosis who underwent a TAVI procedure that was complicated postoperatively by hectic fever without an identified source of infection. After excluding all possible causes of fever, a diagnosis of post-implantation syndrome was made, and glucocorticosteroid therapy led to the patient's recovery.

Discussion. A systemic inflammatory response may occur after endovascular aortic aneurysm repair in some patients. This inflammatory response is called postimplantation syndrome and includes fatigue or other flu-like symptoms, fever, and laboratory signs of inflammation. Our case describes the difficulties in differential diagnosis of post-implantation syndrome as a possible complication of TAVI, and also demonstrates the importance of a multidisciplinary approach to such patients.

About the Authors

Z. G. Tatarintseva
Research Institute — Ochapovsky Regional Clinical Hospital № 1; Kuban State Medical University
Russian Federation

Zoya G. Tatarintseva — Candidate of Medical Sciences, Assistant of the Department of Cardiac Surgery and Cardiology of the Faculty of Advanced Training and Professional Retraining of Specialists of the Kuban State Medical University, Head of the Department of Cardiology, State Budgetary Institution of Health "Scientific Research Institute - Regional Clinical Hospital No. S. V. Ochapovsky”

Krasnodar



K. A. Kazaryants
Research Institute — Ochapovsky Regional Clinical Hospital № 1
Russian Federation

Karina A. Kazaryants — cardiologist

Krasnodar



N. V. Chumachenko
Research Institute — Ochapovsky Regional Clinical Hospital № 1
Russian Federation

Natalia V. Chumachenko — Candidate of Medical Sciences, cardiologist

Krasnodar



K. O. Barbuhatti
Research Institute — Ochapovsky Regional Clinical Hospital № 1; Kuban State Medical University
Russian Federation

Kirill O. Barbuhatti — Doctor of Medical Sciences, Professor, Cardiac Surgeon, Head of the Department of Cardiac Surgery, Research Institute-KKB No. 1 named after. S. V. Ochapovsky”, Head of the Department of Cardiac Surgery and Cardiology of the Faculty of Training and Teaching Staff of Kuban State Medical University

Krasnodar



E. D. Kosmacheva
Research Institute — Ochapovsky Regional Clinical Hospital № 1; Kuban State Medical University
Russian Federation

Elena D. Kosmacheva — Doctor of Medical Sciences, Professor, Head of the Department of Therapy No. 1 of the Faculty of Advanced Training and Professional Retraining of Specialists of the Kuban State Medical University, Deputy Chief Physician for the Medical Department of the Scientific Research Institute - Regional Clinical Hospital No. S. V. Ochapovsky”

Krasnodar



A. S. Tochenaya
Kuban State Medical University
Russian Federation

Arina S. Tochenaya — Resident of the 2nd year of the Department of Therapy No. 1 of the Faculty of Advanced Training and Professional Retraining of Specialists “Kuban State Medical University”

Krasnodar



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Supplementary files

  • Post-implantation syndrome (PIS) is a systemic inflammatory reaction occurring early after endovascular aortic valve implantation.
  • The pathophysiology underlying PIS is still not fully understood.
  • Type of valve implanted may play a role in determining this inflammatory response. Current literature provides low evidence and no established algorithm regarding the type and duration of treatment for PIS.
  • High glucocorticoid doses for PIS in some cases leads to a reduction of the inflammatory response with faster recovery of patients.

Review

For citations:


Tatarintseva Z.G., Kazaryants K.A., Chumachenko N.V., Barbuhatti K.O., Kosmacheva E.D., Tochenaya A.S. Systemic inflammatory response after transcatheter aortic valve replacement: a case report. Russian Journal of Cardiology. 2024;29(3S):5936. (In Russ.) https://doi.org/10.15829/15604071-2024-5936. EDN: TCTGNT

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ISSN 1560-4071 (Print)
ISSN 2618-7620 (Online)