Comparative analysis of left ventricular strain parameters in patients with heart failure of ischemic and non-ischemic genesis
https://doi.org/10.15829/1560-4071-2022-5085
Abstract
Aim. To carry out a comparative analysis of left ventricular (LV) strain parameters, determined by the two-dimensional strain imaging in patients with heart failure (HF) with LV ejection fraction (EF) ≤35%, depending on the origin of HF.
Material and methods. The study included 133 patients with NYHA class 3-4 HF with LVEF ≤35%, taking optimal therapy. Based on the HF origin, 2 following groups of patients were formed: ischemic cardiomyopathy (ICM) (n=70), nonischemic cardiomyopathy (NICM) (n=63). All patients underwent speckle-tracking echocardiography.
Results. All patients included in the study showed significant alterations in longitudinal strain parameters in most myocardial segments, most pronounced in the basal and middle parts of the LV. Comparative analysis of the peak systolic longitudinal strain showed the worst characteristics in patients with ICM were found in the apical segments (p=0,008), and in patients with NICM, in the basal segments of the LV (p=0,046). The studied groups had comparable LV global longitudinal and circumferential strain (p=0,26; p=0,67; respectively).
Conclusion. Groups of patients with HF of ischemic and non-ischemic origin, despite comparable LVEF values, differ in the distribution of the decrease in local longitudinal strain of LV segments. The worst strain characteristics in patients with ICM and NICM are detected in LV apical and basal segments, respectively.
About the Authors
N. N. Ilov
Astrakhan State Medical University; Federal Center for Cardiovascular Surgery
Russian Federation
Competing Interests:
Russian Federation
Nikolay Nikolaevich Ilov - Associate Professor of the department of cardiovascular surgery, Cardiovascular surgeon, M.D.
Astrakhan
Competing Interests:
все авторы заявляют об отсутствии потенциального конфликта интересов, требующего раскрытия в данной статье
D. R. Stompel
Astrakhan State Medical University; Federal Center for Cardiovascular Surgery
Russian Federation
Competing Interests:
Russian Federation
Dinara Rafailovna Stompel - head of the department of functional diagnostics.
Astrakhan
Competing Interests:
все авторы заявляют об отсутствии потенциального конфликта интересов, требующего раскрытия в данной статье
S. A. Boytsov
E.I. Chazov National Medical Research Center of Cardiology
Russian Federation
Competing Interests:
Russian Federation
SergeyAnatolievich Boytsov - Director of the National Medical Research Center of Cardiology of the RBoytsovussian Ministry of Healthcare, Moscow, MD, PhD, Professor, Academician of the Russian Academy of Sciences.
Moscow
Competing Interests:
все авторы заявляют об отсутствии потенциального конфликта интересов, требующего раскрытия в данной статье
O. V. Palnikova
Federal Center for Cardiovascular Surgery
Russian Federation
Competing Interests:
Russian Federation
Olesya Viktorovna Palnikov - cardiologist of the department of surgical treatment of complex arrhythmias and pacemaker implantations.
Astrakhan
Competing Interests:
все авторы заявляют об отсутствии потенциального конфликта интересов, требующего раскрытия в данной статье
A. A. Nechepurenko
Federal Center for Cardiovascular Surgery
Russian Federation
Competing Interests:
Russian Federation
Anatoly Anatolievich Nechepurenko - head of the department of surgical treatment of complex arrhythmias and pacemaker implantations, M.D..
Astrakhan
Competing Interests:
все авторы заявляют об отсутствии потенциального конфликта интересов, требующего раскрытия в данной статье
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For citations:
Ilov N.N., Stompel D.R., Boytsov S.A., Palnikova O.V., Nechepurenko A.A. Comparative analysis of left ventricular strain parameters in patients with heart failure of ischemic and non-ischemic genesis. Russian Journal of Cardiology. 2022;27(12):5085. (In Russ.) https://doi.org/10.15829/1560-4071-2022-5085
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