International register “Dynamics analysis of comorbidities in SARS-CoV-2 survivors” (AKTIV SARS-CoV-2): analysis of 1,000 patients
https://doi.org/10.15829/29/1560-4071-2020-4165
Abstract
COVID-19 is a severe infection with high mortality. The concept of the disease has been shaped to a greater extent on the basis of large registers from the USA, Spain, Italy, and China. However, there is no information on the disease characteristics in Caucasian patients.
Therefore, we created an international register with the estimated capacity of 5,000 patients — Dynamics Analysis of Comorbidities in SARS-CoV-2 Survivors (AKTIV SARS-CoV-2), which brought together professionals from the Russian Federation, Republic of Armenia, Republic of Kazakhstan, and Kyrgyz Republic. The article presents the first analysis of the register involving 1,003 patients. It was shown that the most significant difference of the Caucasian population was the higher effect of multimorbidity on the mortality risk vs other registers. More pronounced effect on mortality of such diseases as diabetes, obesity, hypertension, chronic kidney disease, and age over 60 years was also revealed.
About the Authors
G. P. ArutyunovRussian Federation
Competing Interests:
No.
E. I. Tarlovskaya
Russian Federation
Competing Interests: No.
A. G. Arutyunov
Russian Federation
Competing Interests: No.
Y. N. Belenkov
Russian Federation
Competing Interests: No.
A. O. Konradi
Russian Federation
Competing Interests: No.
Y. M. Lopatin
Russian Federation
Competing Interests: No.
S. N. Tereshchenko
Russian Federation
Competing Interests: No.
A. P. Rebrov
Russian Federation
Competing Interests: No.
A. I. Chesnikova
Russian Federation
Competing Interests: No.
I. V. Fomin
Russian Federation
Competing Interests: No.
N. V. Grigorieva
Russian Federation
Competing Interests: No.
M. V. Boldina
Russian Federation
Competing Interests: No.
A. R. Vaisberg
Russian Federation
Competing Interests: No.
A. S. Blagonravova
Russian Federation
Competing Interests: No.
E. V. Makarova
Russian Federation
Competing Interests: No.
I. I. Shaposhnik
Russian Federation
Competing Interests: No.
T. Yu. Kuznetsova
Russian Federation
Competing Interests: No.
S. V. Malchikova
Russian Federation
Competing Interests: No.
D. N. Protsenko
Russian Federation
Competing Interests: No.
A. V. Evzerikhina
Russian Federation
Competing Interests: No.
M. M. Petrova
Russian Federation
Competing Interests: No.
I. V. Demko
Russian Federation
Competing Interests: No.
D. V. Saphonov
Russian Federation
Competing Interests: No.
H. G. Hayrapetyan
Armenia
Competing Interests: No.
A. S. Galyavich
Russian Federation
Competing Interests: No.
Z. F. Kim
Russian Federation
Competing Interests: No.
A. B. Sugraliev
Kazakhstan
Competing Interests: No.
S. V. Nedogoda
Russian Federation
Competing Interests: No.
V. V. Tsoma
Russian Federation
Competing Interests: No.
S. A. Sayganov
Russian Federation
Competing Interests: No.
V. V. Gomonova
Russian Federation
Competing Interests: No.
I. V. Gubareva
Russian Federation
Competing Interests: No.
A. Sh. Sarybaev
Kyrgyzstan
Competing Interests: No.
E. V. Koroleva
Russian Federation
Competing Interests: No.
O. E. Vilkova
Russian Federation
Competing Interests: No.
I. Y. Fomina
Russian Federation
Competing Interests: No.
I. A. Pudova
Russian Federation
Competing Interests: No.
D. V. Soloveva
Russian Federation
Competing Interests: No.
N. V. Kiseleva
Russian Federation
Competing Interests: No.
N. V. Zelyaeva
Russian Federation
Competing Interests: No.
I. M. Kouranova
Russian Federation
Competing Interests: No.
V. A. Pogrebetskaya
Russian Federation
Competing Interests: No.
F. N. Muradova
Russian Federation
Competing Interests: No.
O. Y. Badina
Russian Federation
Competing Interests: No.
O. V. Kovalishena
Russian Federation
Competing Interests: No.
E. A. Galova
Russian Federation
Competing Interests: No.
S. S. Plastinina
Russian Federation
Competing Interests: No.
N. A. Lyubavina
Russian Federation
Competing Interests: No.
N. N. Vezikova
Russian Federation
Competing Interests: No.
V. I. Levankova
Russian Federation
Competing Interests: No.
S. Yu. Ivanova
Russian Federation
Competing Interests: No.
A. N. Ermilova
Russian Federation
Competing Interests: No.
R. G. Muradyan
Russian Federation
Competing Interests: No.
R. V. Gostishev
Russian Federation
Competing Interests: No.
E. P. Tikhonova
Russian Federation
Competing Interests: No.
T. Y. Kuzmina
Russian Federation
Competing Interests: No.
I. A. Soloveva
Russian Federation
Competing Interests: No.
A. Yu. Kraposhina
Russian Federation
Competing Interests: No.
M. I. Kolyadich
Russian Federation
Competing Interests: No.
T. P. Kolchinskaya
Russian Federation
Competing Interests: No.
V. V. Genkel
Russian Federation
Competing Interests: No.
A. S. Kuznetsova
Russian Federation
Competing Interests: No.
M. V. Kazakovtseva
Russian Federation
Competing Interests: No.
A. A. Odegova
Russian Federation
Competing Interests: No.
T. I. Chudinovskikh
Russian Federation
Competing Interests: No.
S. V. Baramzina
Russian Federation
Competing Interests: No.
N. A. Rozanova
Russian Federation
Competing Interests: No.
A. Sh. Kerimova
Russian Federation
Competing Interests: No.
N. A. Krivosheina
Russian Federation
Competing Interests: No.
S. Y. Chukhlova
Russian Federation
Competing Interests: No.
A. A. Levchenko
Russian Federation
Competing Interests: No.
H. G. Avoyan
Armenia
Competing Interests: No.
K. K. Azarian
Armenia
Competing Interests: No.
Sh. N. Musaelian
Armenia
Competing Interests: No.
S. A. Avetisian
Armenia
Competing Interests: No.
M. E. Levin
Russian Federation
Competing Interests: No.
O. V. Karpov
Russian Federation
Competing Interests: No.
F. M. Sokhova
Russian Federation
Competing Interests: No.
L. A. Burygina
Russian Federation
Competing Interests: No.
T. V. Sheshina
Russian Federation
Competing Interests: No.
A. A. Tiurin
Russian Federation
Competing Interests: No.
O. Yu. Dolgikh
Russian Federation
Competing Interests: No.
E. V. Kazymova
Russian Federation
Competing Interests: No.
D. Yu. Konstantinov
Russian Federation
Competing Interests: No.
O. A. Chumakova
Russian Federation
Competing Interests: No.
O. V. Kondriakova
Russian Federation
Competing Interests: No.
K. Yu. Shishkov
Russian Federation
Competing Interests: No.
T. S. Fil
Russian Federation
Competing Interests: No.
N. A. Prokofeva
Russian Federation
Competing Interests: No.
M. P. Konoval
Russian Federation
Competing Interests: No.
A. A. Simonov
Russian Federation
Competing Interests: No.
A. M. Bitieva
Russian Federation
Competing Interests: No.
N. A. Trostianetckaia
Russian Federation
Competing Interests: No.
M. B. Cholponbaeva
Kyrgyzstan
Competing Interests: No.
Zh. B. Kerimbekova
Kyrgyzstan
Competing Interests: No.
M. Y. Duyshobayev
Kyrgyzstan
Competing Interests: No.
A. Ch. Akunov
Kyrgyzstan
Competing Interests: No.
N. A. Kushubakova
Kyrgyzstan
Competing Interests: No.
E. S. Melnikov
Russian Federation
Competing Interests: No.
E. S. Kim
Russian Federation
Competing Interests: No.
S. Y. Sherbakov
Russian Federation
Competing Interests: No.
D. A. Trofimov
Russian Federation
Competing Interests: No.
D. S. Evdokimov
Russian Federation
Competing Interests: No.
D. A. Ayipova
Kyrgyzstan
Competing Interests: No.
I. A. Duvanov
Russian Federation
Competing Interests: No.
A. K. Abdrahmanova
Kazakhstan
Competing Interests: No.
G. T. Aimakhanova
Kazakhstan
Competing Interests: No.
Sh. O. Ospanova
Kazakhstan
Competing Interests: No.
G. M. Dabylova
Kazakhstan
Competing Interests: No.
A. T. Tursunova
Kazakhstan
Competing Interests: No.
D. S. Xaskaeva
Russian Federation
Competing Interests: No.
A. A. Tulichev
Russian Federation
Competing Interests: No.
E. Yu. Ashina
Russian Federation
Competing Interests: No.
V. A. Kordukova
Russian Federation
Competing Interests: No.
O. Yu. Barisheva
Russian Federation
Competing Interests: No.
K. E. Egorova
Russian Federation
Competing Interests: No.
D. D. Varlamova
Russian Federation
Competing Interests: No.
T. V. Kuprina
Russian Federation
Competing Interests: No.
E. V. Pahomova
Russian Federation
Competing Interests: No.
N. Yu. Kurchugina
Russian Federation
Competing Interests: No.
I. A. Frolova
Russian Federation
Competing Interests: No.
K. V. Mazalov
Russian Federation
Competing Interests: No.
A. K. Subbotin
Russian Federation
Competing Interests: No.
N. A. Kamardina
Russian Federation
Competing Interests: No.
N. V. Zarechnova
Russian Federation
Competing Interests: No.
E. M. Mamutova
Russian Federation
Competing Interests: No.
L. A. Smirnova
Russian Federation
Competing Interests: No.
A. V. Klimova
Russian Federation
Competing Interests: No.
L. D. Shakhgildyan
Russian Federation
Competing Interests: No.
D. S. Tokmin
Russian Federation
Competing Interests: No.
D. I. Tupitsin
Russian Federation
Competing Interests: No.
T. V. Kriukova
Russian Federation
Competing Interests: No.
N. A. Rakov
Russian Federation
Competing Interests: No.
D. S. Polyakov
Russian Federation
Competing Interests: No.
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Review
For citations:
Arutyunov G.P., Tarlovskaya E.I., Arutyunov A.G., Belenkov Y.N., Konradi A.O., Lopatin Y.M., Tereshchenko S.N., Rebrov A.P., Chesnikova A.I., Fomin I.V., Grigorieva N.V., Boldina M.V., Vaisberg A.R., Blagonravova A.S., Makarova E.V., Shaposhnik I.I., Kuznetsova T.Yu., Malchikova S.V., Protsenko D.N., Evzerikhina A.V., Petrova M.M., Demko I.V., Saphonov D.V., Hayrapetyan H.G., Galyavich A.S., Kim Z.F., Sugraliev A.B., Nedogoda S.V., Tsoma V.V., Sayganov S.A., Gomonova V.V., Gubareva I.V., Sarybaev A.Sh., Koroleva E.V., Vilkova O.E., Fomina I.Y., Pudova I.A., Soloveva D.V., Kiseleva N.V., Zelyaeva N.V., Kouranova I.M., Pogrebetskaya V.A., Muradova F.N., Badina O.Y., Kovalishena O.V., Galova E.A., Plastinina S.S., Lyubavina N.A., Vezikova N.N., Levankova V.I., Ivanova S.Yu., Ermilova A.N., Muradyan R.G., Gostishev R.V., Tikhonova E.P., Kuzmina T.Y., Soloveva I.A., Kraposhina A.Yu., Kolyadich M.I., Kolchinskaya T.P., Genkel V.V., Kuznetsova A.S., Kazakovtseva M.V., Odegova A.A., Chudinovskikh T.I., Baramzina S.V., Rozanova N.A., Kerimova A.Sh., Krivosheina N.A., Chukhlova S.Y., Levchenko A.A., Avoyan H.G., Azarian K.K., Musaelian Sh.N., Avetisian S.A., Levin M.E., Karpov O.V., Sokhova F.M., Burygina L.A., Sheshina T.V., Tiurin A.A., Dolgikh O.Yu., Kazymova E.V., Konstantinov D.Yu., Chumakova O.A., Kondriakova O.V., Shishkov K.Yu., Fil T.S., Prokofeva N.A., Konoval M.P., Simonov A.A., Bitieva A.M., Trostianetckaia N.A., Cholponbaeva M.B., Kerimbekova Zh.B., Duyshobayev M.Y., Akunov A.Ch., Kushubakova N.A., Melnikov E.S., Kim E.S., Sherbakov S.Y., Trofimov D.A., Evdokimov D.S., Ayipova D.A., Duvanov I.A., Abdrahmanova A.K., Aimakhanova G.T., Ospanova Sh.O., Dabylova G.M., Tursunova A.T., Xaskaeva D.S., Tulichev A.A., Ashina E.Yu., Kordukova V.A., Barisheva O.Yu., Egorova K.E., Varlamova D.D., Kuprina T.V., Pahomova E.V., Kurchugina N.Yu., Frolova I.A., Mazalov K.V., Subbotin A.K., Kamardina N.A., Zarechnova N.V., Mamutova E.M., Smirnova L.A., Klimova A.V., Shakhgildyan L.D., Tokmin D.S., Tupitsin D.I., Kriukova T.V., Rakov N.A., Polyakov D.S. International register “Dynamics analysis of comorbidities in SARS-CoV-2 survivors” (AKTIV SARS-CoV-2): analysis of 1,000 patients. Russian Journal of Cardiology. 2020;25(11):4165. https://doi.org/10.15829/29/1560-4071-2020-4165