Ascending aortic aneurysm: propensity score matching analysis of hemiarch and non-hemiarch replacement
https://doi.org/10.15829/1560-4071-2020-3887
Abstract
Aim. To compare the shortand medium-term outcomes of hemiarch and nonhemiarch replacement for ascending aortic aneurysm (AAA).
Material and methods. The study included 151 patients with non-syndromic AAA who underwent an elective replacement. Patients were divided into two groups: group 1 (non-hemiarch, n=40) — standard ascending aortic replacement; group 2 (hemiarch, n=111) — ascending aortic replacement with the hemiarch anastomosis in conditions of moderate hypothermia and circulatory arrest with unilateral antegrade cerebral perfusion. To eliminate systematic differences between the compared groups, the propensity score matching (PSM) method was used.
Results. Before PSM, there were no significant intergroup differences in the incidence of neurological complications, myocardial infarction, prolonged ventilation, or acute kidney injury. Bleeding-related reoperation rates and hospital mortality significantly differed between groups. After pseudo-randomization between the non-hemiarch and hemiarch groups, there were no significant differences in the incidence of neurological events, myocardial infarction, prolonged ventilation, reoperations for bleeding, acute renal injury, and hospital mortality. Median-term survival and freedom from aortic reoperations also did not show significant intergroup differences.
Conclusion. Hemiarch replacement for AAA does not lead to an increase in the incidence of postoperative complications, as well as the risk of shortand mediumterm mortality compared with non-hemiarch.
About the Authors
B. N. KozlovRussian Federation
Tomsk
Competing Interests: не заявляет
D. S. Panfilov
Russian Federation
Tomsk
Competing Interests: не заявляет
E. L. Sonduev
Russian Federation
Tomsk
Competing Interests: не заявляет
V. L. Lukinov
Russian Federation
Novosibirsk
Competing Interests: не заявляет
References
1. McClure RS, Brogly SB, Lajkosz K, et al. Epidemiology and management of thoracic aortic dissections and thoracic aortic aneurysms in Ontario, Canada: A population-based study. J Thorac Cardiovasc Surg. 2018;155(6):2254-64. doi:10.1016/j.jtcvs.2017.11.105.
2. Olsson C, Thelin S, Ståhle E, et al. Thoracic aortic aneurysm and dissection: increasing prevalence and improved outcomes reported in a nationwide population-based study of more than 14000 cases from 1987 to 2002. Circulation. 2006;114:2611-8. doi:10.1161/circulationaha.106.630400.
3. Goel N, Jain D, Savlania A, Bansal A. Thoracoabdominal Aortic Aneurysm Repair: What Should the Anaesthetist Know? Turk J Anaesthesiol Reanim. 2019;47(1):1-11. doi:10.5152/TJAR.2018.39129.
4. Singh R, Yamanaka K, Reece BT. Hemiarch: The Real Operation for Ascending Aortic Aneurysm. Seminars in Cardiothoracic and Vascular Anesthesia. 2016;20(4):303-6. doi:10.1177/1089253216672438.
5. Belov YuV, Charchyan ER. Method of radical ascending aorta grafting using the original technique of “open” distal anastomosis. Kardiologiya i Serdechno-Sosudistaya Khirurgiya. 2009;1:10-1. (In Russ.)
6. Kozlov BN, Panfilov DS, Ponomarenko IV, et al. The new technique of unilateral antegrade cerebral perfusion during aortic arch surgery. Kardiologiya i Serdechno-Sosudistaya Khirurgiya. 2015;8(1):30-4. (In Russ.). doi:10.17116/kardio20158130-34.
7. Kozlov BN, Panfilov DS, Gorokhov AS, et al. Results of radical reconstruction of thoracic aortic aneurysms using hemi-arch technique. Kardiologiya i Serdechno-Sosudistaya Khirurgiya. 2016;9(1):42-6. (In Russ.). doi:10.17116/kardio20169142-46.
8. Czerny M, Schmidli J, Adler S, et al. Current options and recommendations for the treatment of thoracicaortic pathologies involving the aortic arch: an expert consensus document of the European Association for Cardio-Thoracic surgery (EACTS) and the European Society for Vascular Surgery (ESVS). Eur J Vasc Endovasc Surg. 2019;57(2):16598. doi:10.1016/j.ejvs.2018.09.016.
9. Rylski B, Pacini D, Beyersdorf F. Standards of reporting in open and endovascular aortic surgery (STORAGE guidelines). European Journal of Cardio-Thoracic Surgery. 2019;56(1):10-20. doi:10.1093/ejcts/ezz145.
10. Hiratzka LF, Bakris GL, Beckman JA, et al. Guidelines for the diagnosis and management of patients with thoracic aortic disease: A report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines, American Association for Thoracic Surgery, American College of Radiology, American Stroke Association, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of Thoracic Surgeons, and Society for Vascular Medicine. Circulation. 2014;35(41):2873-926. doi:10.1161/CIR.0b013e3181d4739e.
11. Park CB, Greason KL, Suri RM, et al. Should the proximal arch be routinely replaced in patients with bicuspid aortic valve disease and ascending aortic aneurysm? J Thorac Cardiovasc Surg. 2011;142:602-7. doi:10.1016/j.jtcvs.2010.08.086.
12. Waldo KL, Hutson MR, Ward CC, et al. Secondary heart field contributes myocardium and smooth muscle to the arterial pole of the developing heart. Dev Biol. 2005;281(1):78-90. doi:10.1016/j.ydbio.2005.02.012.
13. Cheung C, Bernardo AS, Trotter MW, et al. Generation of human vascular smooth muscle subtypes provides insight into embryological origin-dependent disease susceptibility. Nat Biotechnol. 2012;30(2):165-73. doi:10.1038/nbt.2107.
14. Dougenis D, Daily BB, Kouchoukos NT. Reoperations on the aortic root and ascending aorta. Ann Thorac Surg. 1997;64(4):986-92. doi:10.1016/s0003-4975(97)00626-7.
15. Sandhu HK, Tanaka A, Zaidi ST, et al. Impact of redo sternotomy on proximal aortic repair: Does previous aortic repair affect outcomes? J Thorac Cardiovasc Surg. 2020;159(5):1683-91. doi:10.1016/j.jtcvs.2019.04.089.
16. Malaisrie SC, Duncan BF, Mehta CK, et al. The addition of hemiarch replacement to aortic root surgery does not affect safety. J Thorac Cardiovasc Surg. 2015;150(1):118-24. doi:10.1016/j.jtcvs.2015.03.020.
17. Preventza O, Coselli JS, Price MD, et al. Elective primary aortic root replacement with and without hemiarch repair in patients with no previous cardiac surgery. J Thorac Cardiovasc Surg. 2017;153:1402-8. doi:10.1016/j.jtcvs.2016.10.076.
18. Sultan I, Bianco V, Yazji I, et al. Hemiarch reconstruction versus clamped aortic anastomosis for concomitant ascending aortic aneurysm. Ann Thorac Surg. 2018;106:750-6. doi:10.1016/j.athoracsur.2018.03.078.
19. Kilic A, Arnaoutakis GJ, Bavaria JE, et al. Outcomes of elective aortic hemiarch reconstruction for aneurysmal disease in the elderly. Ann Thorac Surg. 2017;104:152230. doi:10.1016/j.athoracsur.2017.03.067.
Review
For citations:
Kozlov B.N., Panfilov D.S., Sonduev E.L., Lukinov V.L. Ascending aortic aneurysm: propensity score matching analysis of hemiarch and non-hemiarch replacement. Russian Journal of Cardiology. 2020;25(10):3887. (In Russ.) https://doi.org/10.15829/1560-4071-2020-3887