Five-year changes of somatic risk factors and comorbidities in patients with angina of effort
https://doi.org/10.15829/1560-4071-2020-2-3730
Abstract
Aim. To assess five-year changes of somatic risk factors and comorbidities in patients with angina of effort.
Material and methods. The study included 320 patients (143 men and 177 women aged 40-69 years) with coronary artery disease (CAD), class I-III angina of effort. Patients underwent examinations in 2012 in three medical centers of the Republic of Ingushetia (Russia), and in 2017 they were invited for a second complex examination with questionnaires, biochemical analysis, and instrumentation.
Results. Over the five-year follow-up, there was an increase of men with class III effort angina up to 45%; a similar trend was observed in women. Both men and women experienced a three-fold increase in the incidence of type 2 diabetes. Initially and during the follow-up, chronic obstructive pulmonary disease was diagnosed 2 times more often in men than in women, which may be associated with smoking. A small increase in the total cholesterol level was recorded in the cohort; among women, these changes were significant. Target levels reach no more than 20% of patients. A significant increase of blood glucose levels over the 5-year period was observed in a cohort of men and women with effort angina.
Conclusion. Over the 5-year follow-up, there was a clinical deterioration of the effort angina, which is associated with an increase in the incidence of some somatic diseases and the severity of the main behavioral and biological risk factors.
About the Authors
Р. О. Ugurchieva
National Medical Research Center for Preventive Medicine
Russian Federation
Magas
Russian Federation
Magas
R. Т. Didigova
National Medical Research Center for Preventive Medicine
Russian Federation
Magas
Russian Federation
Magas
M. B. Khudyakov
Ingush State University
Russian Federation
Moscow
Russian Federation
Moscow
M. N. Mamedov
Ingush State University
Russian Federation
Moscow
Russian Federation
Moscow
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Review
For citations:
Ugurchieva Р.О., Didigova R.Т., Khudyakov M.B., Mamedov M.N. Five-year changes of somatic risk factors and comorbidities in patients with angina of effort. Russian Journal of Cardiology. 2020;25(2):3730. (In Russ.) https://doi.org/10.15829/1560-4071-2020-2-3730
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