Long-term mortality risk in hospitalized patients with heart failure after myocardial infarction

Abstract

Aim. Comparative assessment of laboratory and instrumental parameters of patients with heart failure (HF) after myocardial infarction at admission and discharge from the hospital to determine the long-term mortality risk.

Material and methods. The clinical outcomes of 117 patients with stage II-III  (Strazhesko-Vasilenko Classification) heart failure (64 men and 53 women) were studied. All patients admitted to the hospital underwent laboratory and instrumental examination. The average follow-up for patients after discharge from the hospital was 3 years (12 to 44 months). The long-term mortality risks of HF patients were compared according to the examination data upon admission and discharge from the hospital.

Results. The long-term mortality risk factors of HF patients at admission are the levels of pro-brain natriuretic peptide (proBNP) (risk 1,08, p=0,001), D-dimer (risk 1,062, p=0,018), urea (risk 1,048, p=0,016), creatinine (risk 1,006, p=0,016), alanine transaminase (risk 1,002, p=0,009). The long-term mortality risk factors of HF patients at discharge are urea (risk 1,141, p=0,001), N-terminal proBNP (risk 1,101, p=0,002), and the number of neutrophils (risk 1,064, p=0,002).

Conclusion. There is a difference in risk factors for long-term mortality risk of HF patients at admission and discharge from the hospital.