Carotid artery remodelling in patients with chronic obstructive pulmonary disease
https://doi.org/10.15829/1560-4071-2013-1-54-57
Abstract
Aim. To assess the carotid artery (CA) remodelling, using the results of the duplex ultrasound and 24-hour blood pressure monitoring (BPM) in patients with chronic obstructive pulmonary disease (COPD).
Material and methods. In total, 131 participants (patients with COPD, patients with COPD and arterial hypertension (AH), patients with AH, and healthy volunteers) underwent an ultrasound examination (HD11XE scanner,Phillips,USA) and 24-hour BPM (Schiller,Switzerland).
Results. Among patients with isolated COPD, 61,5% had ultrasound signs of carotid angiopathy (increased intima-media thickness, IMT), which was associated with a statistically significant increase in common carotid artery
(CCA) dilatation, CA deformation and atherosclerotic plaques, left ventricular concentric hypertrophy and diastolic dysfunction. According to the 24-hour BPM results, patients with isolated COPD had increased nighttime hypertensive index and disturbed circadian BP profile (non-dipper or night peaker types). IMT was increased only in every second patient with COPD and AH, and in every third AH patient.
Conclusion. Patients with COPD and AH, compared to participants with isolated AH, demonstrated lower daytime BP levels, disturbed circadian BP profile, increased nighttime hypertensive index, and normal values of BP variability.
About the Author
E. G. Akramova
City Central Clinical Hospital No. 18, Kazan, Russia
Russian Federation
Russian Federation
References
1. Huiart L., Ernst P., Suissa S. Cardiovascular morbidity and mortality in COPD. Chest 2005; 128:2640–6.
2. Curkendall S. M., DeLuise C., Jones J. K. et al. Cardiovascular disease in patients with chronic obstructive pulmonary disease, Saskatchewan Canada cardiovascular disease in COPD patients. Ann. Epidemiol. 2006; 16:63–70.
3. Finkelstein J., Cha E., Scharf S. M. Chronic obstructive pulmonary disease as an independent risk factor for cardiovascular morbidity. Int. J. Chron. Obstruct. Pulmon. Dis. 2009; 4:337–49.
4. Chycherina E. N., Milutina O. V. Systemic inflammation and atherosclerosis of common carotid arteries in patients with chronic obstructive pulmonary disease. Clin.med. 2009; 2:18–20. (Чичерина Е. Н., Милютина О. В. Системное воспаление и атеросклероз общих сонных артерий у больных хронической обструктивной болезнью легких.
5. Клиническая медицина 2009; 2:18–20).
6. Iwamoto H., Yokoyama A., Kitahara Y. et al. Airflow limitation in smokers is associated with subclinical atherosclerosis. Am. J. Respir. Crit. Care Med. 2009; 179:35–40.
7. Zadionchenko V. S., Adasheva T. V., Shilova E. V. et al. Clinical and functional characteristics of hypertension in patients with chronic obstructive pulmonary disease. Russ med J 2003; 9:535–8. Russian (Задионченко В. С., Адашева Т. В., Шилова Е. В. и соавт. Клинико-функциональные особенности артериальной гипертонии у больных хроническими обструктивными болезнями легких. Русский медицин-
8. ский журнал 2003; 9:535–38).
9. Ivashkin V. T., Kuznetsov E. N., Drapkina O. M. Clinical value of ambulatory blood pressure monitoring. M.; 2001. Russian (Ивашкин В. Т., Кузнецов Е. Н., Драпкина О. М. Клиническое значение суточного мониторирования артериального давления. М.; 2001).
10. Leluk V. G., Leluk S. E. Cerebral blood flow and blood pressure. M.: Real time; 2004. Russian (Лелюк В. Г., Лелюк С. Э. Церебральное кровообращение и артериальное давление. М.: Реальное время; 2004).
11. De Lucas-Ramos P., Isquierdo-Alonso J. L., Rodriguez-Gonzalez Moro J. M. et al. Cardiovascular risk factors in chronic obstructive pulmonary disease: results of the ARCE study. Arch. Bronconeumol 2008; 44:233–8.
12. Paleev N. R., Raspokina N. A., Fedorova S. I. et al. Is there a “pulmogennaya hypertension?” Cardiology 2002; 6:51–3. Russian (Палеев Н. Р., Распокина Н. А., Федорова С. И. и соавт. Существует ли «пульмогенная гипертензия?». Кардиология 2002; 6:51–3).
13. Mukharliamov N. M., Sattbekov G. S., Suchkov B. V. Systemic hypertension in patients with chronic nonspecific lung diseases. Cardiology 1974; 12:55–61. Russian (Мухарлямов Н. М., Саттбеков Ж. С., Сучков В. В. Системная артериальная гипертензия у больных хроническими неспецифическими заболеваниями легких. Кардиология 1974; 12:55–61).
Review
For citations:
Akramova E.G. Carotid artery remodelling in patients with chronic obstructive pulmonary disease. Russian Journal of Cardiology. 2013;(1):54-57. (In Russ.) https://doi.org/10.15829/1560-4071-2013-1-54-57
Views:
604
Email this article 