Preview

Russian Journal of Cardiology

Advanced search

Mediators of intracellular interactions and endothelial function in myxomatous mitral valve prolapse

https://doi.org/10.15829/1560-4071-2013-1-28-32

Abstract

Aim. To study the selected mediators of intracellular interactions and endothelial function in patients with myxomatous mitral valve prolapse (MVP).

 

Material and methods. In total, 25 patients with myxomatous MVP, aged 18–29 years, were examined. The comparison groups included patients with MVP but no echocardiographic signs of myxomatosis and healthy individuals. The blood levels of the following mediators were measured: interleukin 1

About the Authors

A. V. Yagoda
Stavropol State Medical Academy
Russian Federation


N. N. Gladkikh
Stavropol State Medical Academy
Russian Federation


L. N. Gladkikh
City Polyclinic No. 1
Russian Federation


M. V. Novikova
Stavropol Region Clinical Cardiology Dispanser, Stavropol, Russia.
Russian Federation


G. A. Saneeva
Stavropol State Medical Academy
Russian Federation


References

1. Yagoda A. V., Gladkikh N. N. Small heart anomalies. Stavropol: StGMA izdatelstvo; 2005. Russian (Ягода А. В., Гладких Н. Н. Малые аномалии сердца. Ставрополь: Издательство СтГМА; 2005).

2. Zemtsovsky E. V. Mitral valve prolapse. SPb.: Znanie; 2010. Russian (Земцовский Э. В. Пролапс митрального клапана. СПб.: Знание; 2010).

3. Hereditary disorders of connective tissue. Russian recommendations. Russ J Cardiol 2013; 1 (99), Suppl.1. Russian (Наследственные нарушения соединительной ткани. Российские рекомендации. Российский кардиологический журнал 2013; 1(99), приложение 1).

4. Dem'yanov A. V., Kotov A. Yu. Diagnostic valuable of levels of cytokines in clinical practice. Cytokines and inflammation 2003; 3:20-35. Russian (Демьянов А. В., Котов А. Ю. Диагностическая ценность исследования уровней цитокинов в клинической практике. Цитокины и воспаление 2003, 3:20-35.

5. Pal'zev M. A., Ivanov A. A. Intercellular interactions. M.: Medicine; 1995. Russian (Пальцев М. А., Иванов А. А. Межклеточные взаимодействия. М.: Медицина; 1995).

6. Vtorushina V. V. Immune aspects of small heart anomalies origin: aftoref. … cand. med. sci. M.; 2006. Russian (Вторушина В. В. Иммунные аспекты формирования малых аномалий развития сердца: автореф. … канд. мед. наук М.; 2006).

7. Surkina I. G., Gurevich K. G., Melnik O. O. et al. Increased ability of lymphocyties to produce interferon-

8. The ESC Textbook of cardiovascular medicine / ed. by John Camm A.. Luscher Thomas F., Serruys Patrick W. M.: GEOTAR-Media; 2011. Russian (Болезни сердца и сосудов. Руководство Европейского общества кардиологов / под ред. Джонна Кэмма, Люшера Томаса Ф.,

9. Серруиса Патрика В.; пер. с англ. под ред. Е. В. Шляхто. М.: ГЭОТАР-Медиа; 2011).

10. Wilkenshoff U., Kruk I. Reference of echocardiography. M.; 2007. Russian (Вилкенсхоф У., Крук И. Справочник по эхокардиографии. М.; 2007).

11. Qiao B., Padilla S. R., Benya P. D. Transforming growth factor (TGF)-beta activated kinase 1 mimics and mediates TGF-beta induced stimulation of type II collagen synthesis in chondrocytes independent of Col2

12. Verrecchia F., Chu M. L., Mauviel A. Identification of novel TFG-beta/Smad gene targets in dermal fibroblasts using a combined cDNA microarray/promoter transactivation approach. J Biol Chem. 2001; 276:17058-17062.

13. Akhtar S., Meek K. M., James V. Immunolocalization of elastin, collagen type I and type III, fibronectin, and vitronectin in extracellular matrix components of normal and myxomatous mitral heart valve chordae tendineae. Cardiovasc Pathol 1999; 8:203-211.

14. Bautista L. E., Vera L. M., Arenas I.A. et al. Independent association between inflammatory markers (C-reactive protein, interleukin-6, and TNF-alpha) and essential hypertension. Hum Hypertens 2005; 19:149-154.

15. Tsaregorodtseva T. M., Serova T. I. Cytokines in gastroenterology. M.; 2003. Russian (Царегородцева Т.М., Серова Т. И. Цитокины в гастроэнтерологии. М.; 2003).

16. Barkagan Z. C., Sukhanova G. A. Hemorrhachis mesenchymal dysplasia: a new classification of hemostasis disorders. Thromb Haemost and Reol 2004; 1:14-6. Russian (Баркаган З. С., Суханова Г.А. Геморрагические мезенхимальные дисплазии: новая классификация нарушений гемостаза. Тромбоз, гемостаз и реология 2004, 1:14-6).


Review

For citations:


Yagoda A.V., Gladkikh N.N., Gladkikh L.N., Novikova M.V., Saneeva G.A. Mediators of intracellular interactions and endothelial function in myxomatous mitral valve prolapse. Russian Journal of Cardiology. 2013;(1):28-32. (In Russ.) https://doi.org/10.15829/1560-4071-2013-1-28-32

Views: 611


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1560-4071 (Print)
ISSN 2618-7620 (Online)