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Russian Journal of Cardiology

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Significant improvement of clinical course and reverse myocardial remodeling in young patients with chronic heart failure using cardiac contractility modulation

https://doi.org/10.15829/1560-4071-2019-7-99-102

Abstract

Three clinical cases of 2-year follow-up of young patients with chronic heart failure with a low left ventricular ejection fraction of non-coronarogenic genesis after implantation of the cardiac contractility modulation system are presented. Significant positive dynamics of clinical course and reverse myocardial remodeling according to two-dimensional echocardiography and 2D speckle tracking echocardiography (STE) is shown. The 2D STE technique allowed us to demonstrate the improvement in local contractility of the interventricular septum in the area of implanted electrodes and the remote effect of global contractility improving during 1 year of observation with cardiac contractility modulation.

About the Authors

M. A. Vander
Almazov National Medical Research Centre
Russian Federation

St. Petersburg


Competing Interests: not


E. A. Lyasnikova
Almazov National Medical Research Centre
Russian Federation

St. Petersburg


Competing Interests: not


I. M. Kim
Almazov National Medical Research Centre
Russian Federation

St. Petersburg


Competing Interests: not


T. A. Lelyavina
Almazov National Medical Research Centre
Russian Federation

St. Petersburg


Competing Interests: not


M. Yu. Sitnikova
Almazov National Medical Research Centre
Russian Federation

St. Petersburg


Competing Interests: not


D. S. Lebedev
Almazov National Medical Research Centre
Russian Federation

St. Petersburg


Competing Interests: not


E. N. Mikhailov
Almazov National Medical Research Centre
Russian Federation

St. Petersburg


Competing Interests: not


References

1. Abraham WT, Kuck KH, Goldsmith RL, et al. A randomized controlled trial to evaluate the safety and efficacy of cardiac contractility modulation. JACC Heart Fail. 2018;6:10:874-83. doi:10.1016/j.jchf.2018.04.010.

2. Artukhina EA, Revishvili AS. Implantable devices for cardiomodulation-a new approach in the treatment of heart failure. Niznij Novgorod: Medicinskij al'manach. 2017;3(48):218-20.(In Russ.)


Review

For citations:


Vander M.A., Lyasnikova E.A., Kim I.M., Lelyavina T.A., Sitnikova M.Yu., Lebedev D.S., Mikhailov E.N. Significant improvement of clinical course and reverse myocardial remodeling in young patients with chronic heart failure using cardiac contractility modulation. Russian Journal of Cardiology. 2019;(7):99-102. (In Russ.) https://doi.org/10.15829/1560-4071-2019-7-99-102

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ISSN 1560-4071 (Print)
ISSN 2618-7620 (Online)