Hereditary systemic transthyretin amyloidosis: a clinical case and an opinion on the problem
A. S. Draganova,
A. V. Soboleva,
A. E. Ertman,
T. A. Galanskaya,
E. I. Nikolaychuk,
D. V. Ryzhkova,
E. A. Polyakova,
E. V. Shlyakhto https://doi.org/10.15829/1560-4071-2019-6-136-142
Abstract
This article presents a clinical case of a patient with hereditary systemic hereditary transthyretin amyloidosis. Difficulties of diagnostics and differential diagnostics of this disease are shown in a patient with arterial hypertension, a clinic of angina, coronary artery disease, cardiac rhythm and conduction disturbances, cardiomegaly, heart failure and renal dysfunction. It required a comprehensive approach using the methods of routine clinical and laboratory examination, as well as nuclear cardiology, morphological studies and molecular DNA diagnostics.
About the Authors
A. S. Draganova
I. P. Pavlov First State Medical University of St. Petersburg; V. A. Almazov National Medical Research Center
Russian Federation
St. Petersburg.
Competing Interests: Nothing to declare
Russian Federation
St. Petersburg.
Competing Interests: Nothing to declare
A. V. Soboleva
I. P. Pavlov First State Medical University of St. Petersburg; V. A. Almazov National Medical Research Center
Russian Federation
St. Petersburg.
Competing Interests: Nothing to declare
Russian Federation
St. Petersburg.
Competing Interests: Nothing to declare
A. E. Ertman
I. P. Pavlov First State Medical University of St. Petersburg; V. A. Almazov National Medical Research Center
Russian Federation
St. Petersburg.
Competing Interests: Nothing to declare
Russian Federation
St. Petersburg.
Competing Interests: Nothing to declare
T. A. Galanskaya
V. A. Almazov National Medical Research Center
Russian Federation
St. Petersburg.
Competing Interests: Nothing to declare
Russian Federation
St. Petersburg.
Competing Interests: Nothing to declare
E. I. Nikolaychuk
I. P. Pavlov First State Medical University of St. Petersburg; V. A. Almazov National Medical Research Center
Russian Federation
St. Petersburg.
Competing Interests: Nothing to declare
Russian Federation
St. Petersburg.
Competing Interests: Nothing to declare
D. V. Ryzhkova
V. A. Almazov National Medical Research Center
Russian Federation
St. Petersburg.
Competing Interests: Nothing to declare
Russian Federation
St. Petersburg.
Competing Interests: Nothing to declare
E. A. Polyakova
I. P. Pavlov First State Medical University of St. Petersburg; V. A. Almazov National Medical Research Center
Russian Federation
St. Petersburg.
Competing Interests: Nothing to declare
Russian Federation
St. Petersburg.
Competing Interests: Nothing to declare
E. V. Shlyakhto
I. P. Pavlov First State Medical University of St. Petersburg; V. A. Almazov National Medical Research Center
Russian Federation
St. Petersburg.
Competing Interests: Nothing to declare
Russian Federation
St. Petersburg.
Competing Interests: Nothing to declare
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Review
For citations:
Draganova A.S., Soboleva A.V., Ertman A.E., Galanskaya T.A., Nikolaychuk E.I., Ryzhkova D.V., Polyakova E.A., Shlyakhto E.V. Hereditary systemic transthyretin amyloidosis: a clinical case and an opinion on the problem. Russian Journal of Cardiology. 2019;(6):136-142. (In Russ.) https://doi.org/10.15829/1560-4071-2019-6-136-142
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