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Cardiovascular events follow-up analysis in patients with sinus node dysfunction and implanted pacemaker

https://doi.org/10.15829/1560-4071-2019-2-53-57

Abstract

Dysfunction of sinus node (DSN) is the syndrome, characterized by symptoms of tissue hypoperfusion and manifestations on the electrocardiogram and could potentially lead to sudden death. The various impact of different types of pacemakers on life quality and cardiovascular endpoints was shown.

Aim. To analyze follow-up cardiovascular endpoints in patients with DSN and installed pacemakers.

Material and methods. Six hundred and ten patients with DSN were analyzed in follow-up period (39,7±0,8 months) for unfavorable cardiovascular events (myocardial infarction, strokes, cardiovascular and non-cardiovascular hospitalizations).

Results. Mortality rate differed depending on DSN variant (p=0,041), and most unfavorable was “tachy-brady” and sinoatrial node arrest + sinus node block III types. Also, the difference in mortality rate was shown for pacing variants (p=0,049) with maximal rate number of deaths was in ventricular pacemakers (24,6%) less — in dual-chamber pacemakers (11,7%) and minimal — in atrial (5,5%). No changes in cardiovascular endpoints was found between groups with sinus and pacemaker’s rhythm (p>0,5).

Conclusion. In the follow-up analyze the difference between cardiovascular endpoints in patients in various types of pacemakers and regimen of stimulation was shown.

About the Authors

E. A. Badykova
Republican Cardiology Center of the Republic of Bashkortostan; Bashkir State Medical University
Russian Federation

Ufa


Competing Interests:

nothing to declare



M. R. Badykov
Republican Cardiology Center of the Republic of Bashkortostan; Bashkir State Medical University

Ufa


Competing Interests:

nothing to declare



V. V. Plechev
Bashkir State Medical University
Russian Federation

Ufa


Competing Interests:

nothing to declare



I. Sh. Sagitov
Republican Cardiology Center of the Republic of Bashkortostan
Russian Federation

Ufa


Competing Interests:

nothing to declare



I. A. Lakman
Ufa State Aviation Technical University
Russian Federation

Competing Interests:

nothing to declare



N. Sh. Zagidullin
Bashkir State Medical University; Ufa State Aviation Technical University
Russian Federation

Competing Interests:

nothing to declare



References

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Review

For citations:


Badykova E.A., Badykov M.R., Plechev V.V., Sagitov I.Sh., Lakman I.A., Zagidullin N.Sh. Cardiovascular events follow-up analysis in patients with sinus node dysfunction and implanted pacemaker. Russian Journal of Cardiology. 2019;(2):53-57. (In Russ.) https://doi.org/10.15829/1560-4071-2019-2-53-57

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ISSN 1560-4071 (Print)
ISSN 2618-7620 (Online)