Radionuclide semiotics of pulmonary hypertension and NO production in children with non-cyanotic heart valve disease
Abstract
Radionuclide assessment of pulmonary hemodynamics was performed in 45 children with congenital heart valve pathology and increased pulmonary blood flow. Radionuclide angiopulmonography was performed at rest and during acute pharmacological tests, before and after valve surgery. Basal and enalapril-stimulated plasma concentrations of stable NO metabolites (nitrite and nitrate anions) were measured. Radionuclide bolus speed dynamics after vasodilatator (niphedipine, enalapril) administration demonstrated pulmonary circulation reserve. Plasma levels of NO metabolites were used in erectile dysfunction verification.
About the Authors
Yu. B. Lishmanov
НИИ кардиологии Томского научного центра СО РАМН, Томск
Russian Federation
Russian Federation
K. V. Zavadovsky
НИИ кардиологии Томского научного центра СО РАМН, Томск
Russian Federation
Russian Federation
S. N. Ivanov
НИИ кардиологии Томского научного центра СО РАМН, Томск
Russian Federation
Russian Federation
T. E. Suslova
НИИ кардиологии Томского научного центра СО РАМН, Томск
Russian Federation
Russian Federation
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Review
For citations:
Lishmanov Yu.B., Zavadovsky K.V., Ivanov S.N., Suslova T.E. Radionuclide semiotics of pulmonary hypertension and NO production in children with non-cyanotic heart valve disease. Russian Journal of Cardiology. 2005;(5):5-11. (In Russ.)
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