CHRONIC EXPERIMENTS STUDYING THE ROLE OF SYMPATHETIC TONE IN REGULATING HEART ACTIVITY
Abstract
Experimental data that have appeared lately are the evidence of the fact that sympathetic nerve exerts constant (tonic) stimulating influence on heart activity, what contradicts to formed (classical) conception on regulation of heart activity by a sympathetic nerve. However experimental data us have worked under conditions of chronical experiment with blocade of sympathetic and parasympathetic nerve system by pharmaceutical medications, on the contrary, confirm classical ideas of the abscence of sympathetic nerve’s tonic influence on heart. According to our data, decrease of frequency of heart contractions in other specialists’ experiments is a result of effects of experiment’s conditions (narcosis’ kind and depth, possible hypothermia, experiment’s duration, sort of pharmaceutical medications). Frequency of heart contractions, as distinct hau the of blood vessels, is assessed in rest by a level of expression of wandering n.vagus tone and humoral substances circulating in blood. Classical concepts of abscence of tone of sympathetic nerves for heart remain in effect.
About the Author
V. M. Smirnov
Российский государственный медицинский университет, Москва
Russian Federation
Russian Federation
References
1. Конради Г.П. Значение эфферентной иннервации сердца. - В кн.: Физиология кровообращения. Физиология сердца. / Л.: Наука, 1980, с.400-411
2. Косицкий Г.И. Физиология человека, / М.: Медицина, 1985, 559 с., ил.
3. Смирнов В. М. Симпатическая нервная система не участвует в развитии ваготомической тахикардии. // Бюлл. эксп. биол. и мед., 1995, СХХ(8): 125-128.
4. Шмидт Р. иТевс Г. Физиология человека, / М.: Мир, 1996, т.2, 331-641с., ил.
5. Battarbee Harold D., Zavecz James H., Betzing Kenneth W. Vagal and sympathetic components of the heart rate reflex in chronic portal vein stenosis. // Amer. J. Physiol., 1995; 296(6, Pt 1): 892-901.
6. Cameron John S. Autonomic nervous tone ans regulation of heart rate in the goldish. Carasius auratus. // Comp.Biochem. and phisiol. 1979; 63(2): 341-349.
7. Donald., Samueloff S., Ferguson D. Mechanism of tachicardia caused by atropin in conscious dogs. // Am.J.Physiol. 1967; 312(4):901-910.
8. Ekblom В., KilbomA., Soltisiac J. Physial training, bradicardia and autonomic nervous system. // Scand. J.Clin. a.Lab. Invest. 1973; 32(3): 215-256.
9. Goldstone B.M., Windhame C.H. Cardiac adaptation to exercise.// Pflyg.Arch. 1967; 295(1): 15-29.
10. Kadazewski W., Widsicomble J.C. The effects of vagotomy, vagal colling and afferent vagal stimulation on breathing and lung mechanism of rabbits. // J.Physiol. 1969; 201(2): 259-270.
11. Keroes J., Ecke R., Rappoport E. Ventricular function ourver in the exercising dog. // Circul.Res. 1969; 25(5): 557-567.
12. Urtuhaler F., Millar F., Burgess M., James M. Comparative dependence on adrenergic neural tone by automaticity in the sinus node. // Pharm.Exp.Therap. 1973; 187(2): 269-279.
Review
For citations:
Smirnov V.M. CHRONIC EXPERIMENTS STUDYING THE ROLE OF SYMPATHETIC TONE IN REGULATING HEART ACTIVITY. Russian Journal of Cardiology. 2001;(2):54-58. (In Russ.)
Views:
837
Email this article 