Metoprolol tartrate and succinate: from chemical structure to clinical effectiveness differences
About the Authors
Yu. B. BelousovRussian Federation
M. V. Leonova
Russian Federation
O. A. Maneshina
Russian Federation
References
1. Theeuwes F. Elementary osmotic pump//J Pharm. Sci. 1975; 64: 1987-1991.
2. Corrigan O.I. The biopharmaceutic drug classification and drugs administered in extended release (ER) formulation//Adv. Exp. Med. Biol. 1997; 423: 111-128.
3. Медведев О.С., Медведева Н.А. Hi-Tech таблетки -почему и зачем?//Трудный пациент. 2005. № 6.
4. A. Sandberg, MSc., B. Abrahamsson, C.G. Regardh, et al. Pharmacokinetic and Biopharmaceutic Aspects of Once Daily Treatment with metoprolol CR/ZOK: A Review Article//J Clin Pharmacol 1990; 30: S2-S16.
5. Lee Y.T., Liau, Wong E.C., et al. Pharmacokinetic and pharmacodynamic comparison of conventional and controlled release formulation of metoprolol in healthy Chinese subjects.
6. Johnsson G., Jordo L., Lundborg P., et al. Plasma levels and pharmacological effects of metoprolol administered as controlled release (Durules) and ordinary tablets in healthy volunteers.
7. Sandberg A., Blomqvist I., Jonsson U.E., et al. Pharmacokinetic and pharmacodynamic properties of a new controlled-release formulation of metoprolol: A comparison with conventional tablets//Eur J Clin Pharmacol 1988; 33 (Suppl): S9.
8. Hogan J.E. Hydroxypropyl methylcellulose sustained release technology//Drug Dev Ind Pharm. 1989; 15(27): 975-999.
9. A. Prakash, A. Markham Metoprolol: A Review of its Use in Chronic Heart failure//Drugs 2000 Sep; 60(3): 647-678.
10. Lucker P., Moore G., Wiselgren I., et al. Pharmacokinetic and pharmacodynamic comparison of metoprolol CR/ZOK once daily with conventional tablets once daily and in divided doses//J Clin Pharmacol 1990; 30 (Suppl): S17-27.
11. Сиренко Ю.Н., Рековец О.Л., Дзяк Г.В. и др. Антигипертензивная эффективность метопролола ретарда у больных с мягкой и умеренной артериальной гипертензиней (результаты многоцентрового исследования «ProlongER»)//Российский кардиологический журнал. 2006. 2(58): 67-72.
12. Warrington S.J., Barclay S.P., John V.A. et al. Comparison of singledose pharmacokinetic and pharmacodynamic properties of two metoprolol Oros systems with different initial zero-order release rates//Br J Clin Pharmacol. 1985; 19 Suppl 2: 225S-230S.
13. Sandberg A., Abrahamsson B., Svenheden A., et al. Steady-state bioavailability and day-to-day variability of a multiple-unit (CR/ZOK) and a single-unit (OROS) delivery system of metoprolol after once-daily dosing//Pharm Res 1993 Jan; 10(1): 28-34.
14. J. Herlitz, M. Dellborg, B. Karlson, et al. Similar Risk Reduction of Death of Extended-Release metoprolol Once Daily and Immediate-Release Metoprolol Twice Daily During 5 Years After Myocardial Infarction//Cardiovasc Drugs and Therapy 1999; 13: 127-135.
15. Olsson G., Tuomilehto J., Berglund G., et al. Primary prevention of sudden cardiac death in hypertensive patients. Mortality results from the MAPHY study//Am J Hypertens 1991; 4: 151-8.
16. Stockholm Metoprolol Trial//J Am Coll Cardiol. 1985.
17. Hjalmarson et al. Goteborg Metoprolol Trial//Am. J. Cardiol 1997; 13: 40J-44J.
18. MIAMI Metoprolol In Acute Myocardial Infarction//Eur. Heart. J. 1985; 6: 199.
19. Waagstein F., Bristow M.R., Swedberg K., et al. Beneficial effects of metoprolol in idiopathic dilated cardiomyopathy. Metoprolol in Dilated Cardiomyopathy (MDC) Trial Study Group [see comments]//Lancet 1993; 342: 1441-6.
20. Carruthers, R. Shearer, W. Taylor, and M. Moore. A comparison of a controlled release (CR/ZOK) formulation of metoprolol, once daily, with conventional metoprolol tablets, twice daily, in mild to moderate hypertension//J Clin Pharmacol 1990; 30: 61.
21. Klein G., Berger J., Olsson G. A double-blind comparison of metoprolol CR/ZOK 50 mg and atenolol 50 mg once daily for uncomplicated hypertension//J Clin Pharmacol 1990; 30: S72-S77.
22. Марцевич С.Ю., Лукина Ю.В., Деев А.Л. и др. Сравнительное изучение нового препарата метопролола тартрата пролонгированного действия -эгилока ретард и оригинального препарата метопролола сукцината -беталока ZOK у больных мягкой и умеренной артериальной гиперторнией//Рациональная фармакотерапия в кардиологии. 2005; 3: 35-40.
Review
For citations:
Belousov Yu.B., Leonova M.V., Maneshina O.A. Metoprolol tartrate and succinate: from chemical structure to clinical effectiveness differences. Russian Journal of Cardiology. 2007;(3):81-85. (In Russ.)